SCHEMBL5483761

SCHEMBL5483761

COP(C)(=O)c1ccc(C)cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.58
LMNA P02545 4/20 0.50
TSHR P16473 2/20 0.50
GAA P10253 3/20 0.45
CYP3A4 P08684 1/20 0.43
ACHE P22303 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5488946 0.80 HPGD (0.52) HPGDLMNATSHRGAACYP3A4
SCHEMBL384926 0.78 HPGD (0.54) HPGDLMNATSHRGAACYP3A4
SCHEMBL3895562 0.78 HPGD (0.54) HPGDLMNATSHRGAACYP3A4
SCHEMBL780147 0.78 CA2 (0.50) LMNAACHETDP1MEN1KMT2A
SCHEMBL5482554 0.77 HPGD (0.48) HPGDLMNATSHRGAACYP3A4
SCHEMBL10237191 0.74 HPGD (0.50) HPGDLMNATSHRGAACYP3A4
SCHEMBL5492110 0.74 HPGD (0.45) HPGDLMNATSHRGAACYP3A4
SCHEMBL2209561 0.74 CA1 (0.50) HPGDTSHRTDP1KMT2AALDH1A1
SCHEMBL5490568 0.74 ACHE (0.42) HPGDLMNAACHETDP1MEN1
SCHEMBL3888438 0.74 HPGD (0.70) HPGDLMNATSHRGAACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117043226-A Polyester compositions comprising tetramethylcyclobutanediol and cyclohexanedimethanol with improved catalyst systems comprising lithium and aluminum atoms 伊士曼化工公司 2023-11-10 CN disclosed
CN-109563252-B Polyester compositions comprising tetramethylcyclobutanediol and ethylene glycol using an improved catalyst system 伊士曼化工公司 2022-04-26 CN disclosed
CN-109563247-B Polyester compositions comprising tetramethylcyclobutanediol and ethylene glycol using an improved catalyst system 伊士曼化工公司 2021-10-08 CN disclosed
US-8765722-B2 Inhibitors of flaviviridae viruses GILEAD SCIENCES, INC. (US) 2014-07-01 US disclosed
US-8765722-B2 Inhibitors of flaviviridae viruses GILEAD SCIENCES, INC. (US) 2014-07-01 US disclosed
US-20130302280-A1 INHIBITORS OF FLAVIVIRIDAE VIRUSES GILEAD SCIENCES, INC. 2013-11-14 US disclosed
US-20130302280-A1 INHIBITORS OF FLAVIVIRIDAE VIRUSES GILEAD SCIENCES, INC. 2013-11-14 US disclosed
US-8501714-B2 Inhibitors of Flaviviridae viruses GILEAD SCIENCES, INC. (US) 2013-08-06 US disclosed
US-20120156166-A1 INHIBITORS OF FLAVIVIRIDAE VIRUSES GILEAD SCIENCES, INC. (US) 2012-06-21 US disclosed
US-20120156166-A1 INHIBITORS OF FLAVIVIRIDAE VIRUSES GILEAD SCIENCES, INC. (US) 2012-06-21 US disclosed
WO-2011031669-A1 INHIBITORS OF FLAVIVIRIDAE VIRUSES GILEAD SCIENCES, INC. (US) 2011-03-17 WO disclosed
US-20070087270-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SOLUTION SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2007-04-19 US disclosed
US-7169511-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2007-01-30 US disclosed
EP-1555711-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY CONTAINING THE SAME Mitsubishi Chemical Corporation (JP) 2005-07-20 EP disclosed
US-20050014071-A1 Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130302280-A1 INHIBITORS OF FLAVIVIRIDAE VIRUSES HAVCR2, CYP2F1, CYP4F3 HPGD 2406/4885LMNA 1554/4885TSHR 4286/4885
US-20120156166-A1 INHIBITORS OF FLAVIVIRIDAE VIRUSES HAVCR2, CYP2F1, CYP4F3 HPGD 2406/4885LMNA 1554/4885TSHR 4286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.