Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL5490727 | 0.91 | KMT2A (0.53) | KMT2AKDM4EHTTGAAMEN1 | |
| Carbamic Acid SCHEMBL5487777 | 0.88 | KMT2A (0.51) | KMT2AKDM4EHTTGAAMEN1 | |
| SCHEMBL5484369 | 0.84 | KMT2A (0.47) | KMT2AKDM4EHTTGAAMEN1 | |
| Carbamic Acid SCHEMBL5490629 | 0.83 | SCN3A (0.61) | KMT2AKDM4EHTTGAASMN1; SMN2 | |
| Carbamic Acid SCHEMBL5491782 | 0.83 | SCN3A (0.52) | KMT2AKDM4EHTTGAAALDH1A1 | |
| Carbamic Acid SCHEMBL5485171 | 0.81 | KMT2A (0.56) | KMT2AKDM4EHTTGAAMEN1 | |
| Carbamic Acid SCHEMBL5484597 | 0.80 | KMT2A (0.60) | KMT2AKDM4EHTTGAAMEN1 | |
| Carbamic Acid SCHEMBL5485774 | 0.78 | KMT2A (0.52) | KMT2AKDM4EHTTGAAMEN1 | |
| SCHEMBL6514406 | 0.76 | HTR2C (0.54) | KMT2AKDM4EHTTGAASMN1; SMN2 | |
| SCHEMBL6510966 | 0.76 | HTR2C (0.54) | KMT2AKDM4EHTTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687259-B1 | CYCLOPENTYL DERIVATES | NEWRON PHARM SPA (IT) | 2007-08-08 | — | — | EP | claimed |