Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | HPD | P32754 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL5490629 | 0.88 | SCN3A (0.61) | SCN3AKDM4EGAAHTTKMT2A | |
| Carbamic Acid SCHEMBL5490536 | 0.88 | ALDH1A1 (0.59) | ALDH1A1PRMT5WDR77KDM4EGAA | |
| Carbamic Acid SCHEMBL5490727 | 0.85 | KMT2A (0.53) | SCN3AKDM4EGAAHTTKMT2A | |
| SCHEMBL5481360 | 0.83 | KCNH2 (0.52) | SCN3AKCNH2HPDMAOBPARP15 | |
| SCHEMBL5481355 | 0.83 | KCNH2 (0.52) | SCN3AKCNH2HPDMAOBPARP15 | |
| SCHEMBL6064341 | 0.83 | KCNH2 (0.52) | SCN3AKCNH2HPDMAOBPARP15 | |
| Carbamic Acid SCHEMBL5487777 | 0.83 | KMT2A (0.51) | SCN3AKDM4EGAAHTTKMT2A | |
| SCHEMBL5481350 | 0.83 | KCNH2 (0.52) | SCN3AKCNH2HPDMAOBPARP15 | |
| Carbamic Acid SCHEMBL5483797 | 0.83 | KMT2A (0.60) | SCN3AALDH1A1KDM4EGAAHTT | |
| Carbamic Acid SCHEMBL5485774 | 0.83 | KMT2A (0.52) | SCN3AALDH1A1KDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687259-B1 | CYCLOPENTYL DERIVATES | NEWRON PHARM SPA (IT) | 2007-08-08 | — | — | EP | claimed |