Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL5485774 | 0.84 | KMT2A (0.52) | KMT2AKDM4EHTTGAAMEN1 | |
| SCHEMBL5482011 | 0.83 | KDM4E (0.46) | KMT2AKDM4EHTTGAACYP1A2 | |
| SCHEMBL5490373 | 0.83 | KDM4E (0.46) | KMT2AKDM4EHTTGAACYP1A2 | |
| SCHEMBL5482016 | 0.83 | KDM4E (0.46) | KMT2AKDM4EHTTGAACYP1A2 | |
| Carbamic Acid SCHEMBL5490629 | 0.83 | SCN3A (0.61) | KMT2AKDM4EHTTGAACYP1A2 | |
| Carbamic Acid SCHEMBL5491782 | 0.82 | SCN3A (0.52) | KMT2AKDM4EHTTGAAALDH1A1 | |
| Carbamic Acid SCHEMBL5490727 | 0.82 | KMT2A (0.53) | KMT2AKDM4EHTTGAAMEN1 | |
| Carbamic Acid SCHEMBL5485171 | 0.80 | KMT2A (0.56) | KMT2AKDM4EHTTGAAMEN1 | |
| Carbamic Acid SCHEMBL5487777 | 0.80 | KMT2A (0.51) | KMT2AKDM4EHTTGAAMEN1 | |
| Carbamic Acid SCHEMBL5483797 | 0.80 | KMT2A (0.60) | KMT2AKDM4EHTTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687259-B1 | CYCLOPENTYL DERIVATES | NEWRON PHARM SPA (IT) | 2007-08-08 | — | — | EP | claimed |