Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477167 | 0.82 | HRH4 (0.36) | HRH4PTGDR2KDM1AARLRRK2 | |
| SCHEMBL5477181 | 0.76 | PDE5A (0.38) | HRH4ARPDE5ANPC1RAB9A | |
| SCHEMBL13564574 | 0.73 | CYP2A6 (0.44) | HRH4 | |
| SCHEMBL5472664 | 0.72 | PDE5A (0.36) | ARPDE5AMEN1RAB9AKMT2A | |
| SCHEMBL5471189 | 0.67 | AR (0.40) | ARMEN1NPC1RAB9AKMT2A | |
| SCHEMBL1260698 | 0.67 | DRD3 (0.35) | PTGDR2LRRK2 | |
| SCHEMBL7335983 | 0.67 | F2 (0.63) | KDM1AARPDE5ALRRK2PDE4D | |
| SCHEMBL548410 | 0.67 | CYP2A6 (0.50) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5468128 | 0.66 | MAPT (0.53) | ARMEN1NPC1RAB9AKMT2A | |
| SCHEMBL5022989 | 0.66 | PDE4A (0.44) | MEN1NPC1RAB9AKMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093548-A1 | Use of progesterone receptor modulators | WYETH (US) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093548-A1 | Use of progesterone receptor modulators | PGR, GNRHR, PGRMC2 | HRH4 1091/4885PTGDR2 28/4885CCNT1 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.