Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.35 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479951 | 0.78 | CYP2A6 (0.40) | AR | |
| SCHEMBL548410 | 0.78 | CYP2A6 (0.50) | NPC1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL5468128 | 0.77 | MAPT (0.53) | ARNPC1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11554110 | 0.74 | CYP2A6 (0.44) | NPC1MEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL313099 | 0.74 | AR (0.51) | ARRAB9ALMNAUSP2PGR | |
| SCHEMBL350999 | 0.74 | AR (0.51) | ARUSP2PGR | |
| SCHEMBL31128553 | 0.74 | AR (0.51) | ARRAB9ALMNAUSP2PGR | |
| SCHEMBL16906004 | 0.72 | ALDH1A1 (0.48) | ARMEN1KMT2AHPGDMAPT | |
| SCHEMBL20282452 | 0.71 | PGR (0.47) | ARPGR | |
| SCHEMBL20282639 | 0.71 | PGR (0.47) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093548-A1 | Use of progesterone receptor modulators | WYETH (US) | 2007-04-26 | — | — | US | claimed |
| US-20070093548-A1 | Use of progesterone receptor modulators | WYETH (US) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093548-A1 | Use of progesterone receptor modulators | PGR, GNRHR, PGRMC2 | AR 104/4885NPC1 4186/4885MEN1 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.