SCHEMBL5483944

SCHEMBL5483944

CC(C)CCCCCCCCCCCCCCCOC(=O)C(O)C(O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.39
RARB P10826 1/20 0.39
GPR84 Q9NQS5 3/20 0.36
FFAR1 O14842 1/20 0.36
KDM4C Q9H3R0 2/20 0.36
TSHR P16473 1/20 0.36
KDM4A O75164 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
MAPT P10636 1/20 0.35
NOD1 Q9Y239 1/20 0.35
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
ACE2 Q9BYF1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29915292 1.00 BLM (0.39) BLMRARBGPR84FFAR1KDM4C
SCHEMBL31396834 1.00 BLM (0.39) BLMRARBGPR84FFAR1KDM4C
SCHEMBL5471739 0.93 RARB (0.39) BLMRARBKDM4CTSHRKDM4A
SCHEMBL3285954 0.93 RARB (0.39) BLMRARBKDM4CTSHRKDM4A
SCHEMBL11330559 0.87 TSHR (0.48) BLMTSHRNOD1CHRM2CHRM4
SCHEMBL28001738 0.85 TSHR (0.42) BLMTSHR
SCHEMBL28411335 0.84 TSHR (0.50) TSHRNOD1
Cadaverine Tartrate SCHEMBL27887855 0.82 TSHR (0.58) BLMRARBTSHR
SCHEMBL41759 0.81 NAAA (0.52) GPR84FFAR1TSHRMAPTNOD1
SCHEMBL17986646 0.81 NAAA (0.52) GPR84FFAR1TSHRMAPTNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10238746-B2 Surfactant-free water-free foamable compositions, breakable foams and gels and their uses FOAMIX PHARMACEUTICALS LTD (IL) 2019-03-26 US claimed
US-20180193469-A1 SURFACTANT-FREE WATER-FREE FOAMABLE COMPOSITIONS, BREAKABLE FOAMS AND GELS AND THEIR USES FOAMIX PHARMACEUTICALS LTD. (IL) 2018-07-12 US claimed
US-8618081-B2 Compositions, gels and foams with rheology modulators and uses thereof FOAMIX LTD. (IL) 2013-12-31 US claimed
WO-2024220589-A2 USES OF PAN BET INHIBITORS CROSS-REFERENCE TO RELATED APPLICATIONS VYNE THERAPEUTICS INC. (US) 2024-10-24 WO disclosed
US-20240325393-A1 TOFACITINIB-CONTAINING ANHYDROUS ELASTOMER-BASED GEL FORMULATIONS VYNE THERAPEUTICS INC. 2024-10-03 US disclosed
US-20230037905-A1 TOPICAL COMPOSITION COMPRISING TOFACITINIB AND FINGOLIMOD VYNE THERAPEUTICS INC. 2023-02-09 US disclosed
CN-114980957-A Metered dose for intraocular or periocular disorders 阿祖拉眼科有限公司 2022-08-30 CN disclosed
CN-114980895-A Metered dose for demodex and related disorders 阿祖拉眼科有限公司 2022-08-30 CN disclosed
CN-114469991-A Selenium disulfide composition for treating meibomian gland dysfunction 阿祖拉眼科有限公司 2022-05-13 CN disclosed
US-11324691-B2 Compositions and methods for treating rosacea and acne JOURNEY MEDICAL CORPORATION (US) 2022-05-10 US disclosed
US-20210205212-A1 COMPOSITIONS AND METHODS FOR TREATING ROSACEA AND ACNE SWK FUNDING LLC 2021-07-08 US disclosed
US-10849847-B2 Compositions and methods for treating rosacea and acne Foamix Pharamaceuticals Ltd. (IL) 2020-12-01 US disclosed
US-10398641-B2 Compositions and methods for treating rosacea and acne FOAMIX PHARMACEUTICALS LTD. (IL) 2019-09-03 US disclosed
US-10322186-B2 Topical tetracycline compositions FOAMIX PHARMACEUTICALS LTD. (IL) 2019-06-18 US disclosed
US-10137200-B2 Surfactant-free water-free foamable compositions, breakable foams and gels and their uses FOAMIX PHARMACEUTICALS LTD. (IL) 2018-11-27 US disclosed
US-20180193469-A1 SURFACTANT-FREE WATER-FREE FOAMABLE COMPOSITIONS, BREAKABLE FOAMS AND GELS AND THEIR USES FOAMIX PHARMACEUTICALS LTD. (IL) 2018-07-12 US disclosed
US-20180064638-A1 COMPOSITIONS AND METHODS FOR TREATING ROSACEA AND ACNE FOAMIX PHARMACEUTICALS LTD. 2018-03-08 US disclosed
US-20070275022-A1 Cosmetic Hair Preparation LION CORPORATION (JP) 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070275022-A1 Cosmetic Hair Preparation CUTA, H1-10, PUF60 BLM 885/4885RARB 495/4885GPR84 3069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.