SCHEMBL548398

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17200968	0.81	HPGD (0.50)	ALDH1A1HPGDHSD17B10CYP1A2THRB
	SCHEMBL28585111	0.79	ALDH1A1 (0.47)	ALDH1A1HPGDHSD17B10CYP1A2THRB
	SCHEMBL7969054	0.78	CYP1A2 (0.60)	ALDH1A1HPGDHSD17B10CYP1A2THRB
	SCHEMBL548399	0.75	HSD17B10 (0.55)	ALDH1A1HPGDHSD17B10CYP1A2THRB
	SCHEMBL275486	0.74	KMT2A (0.53)	ALDH1A1HPGDHSD17B10CYP1A2THRB
	SCHEMBL1666392	0.74	KMT2A (0.48)	ALDH1A1HPGDHSD17B10CYP1A2THRB
	SCHEMBL9930839	0.74	CYP1A2 (0.43)	ALDH1A1HPGDHSD17B10CYP1A2THRB
	SCHEMBL1982386	0.73	HSD17B10 (0.71)	ALDH1A1HPGDHSD17B10CYP1A2THRB
	SCHEMBL7101315	0.73	ALDH1A1 (0.52)	ALDH1A1HPGDHSD17B10CYP1A2THRB
	Benzo[E]Pyrene SCHEMBL27930636	0.72	ALDH1A1 (0.70)	ALDH1A1HPGDHSD17B10CYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.