SCHEMBL5484565

SCHEMBL5484565

FC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCOc1[c]cccc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 1/20 0.37
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
XBP1 P17861 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5488003 0.86 USP2 (0.47) USP2MAPTTSHRCYP1A2CYP2C9
SCHEMBL2238013 0.86
SCHEMBL5487961 0.79
SCHEMBL3079151 0.76 MCHR1 (0.36)
SCHEMBL5491457 0.74 USP2 (0.40) USP2MAPTTSHRCYP1A2CYP2C9
SCHEMBL4530486 0.73 CFTR (0.39) MAPTTSHRL3MBTL1HTTLMNA
SCHEMBL9859940 0.71 USP2 (0.31) USP2MAPTTSHR
SCHEMBL6238419 0.70 JAK2 (0.33) MAPTRECQLHTTLMNAHPGD
SCHEMBL2008537 0.67 KCNH2 (0.32) RECQL
SCHEMBL1407804 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7201950-B2 Optical compensatory sheet, elliptical polarizing plates and liquid-crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-10 US disclosed
US-20040234706-A1 Optical compensatory sheet, elliptical polarizing plates and liquid-crystal display FUJI PHOTO FILM CO., LTD. (JP) 2004-11-25 US disclosed