Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | PEX14 | O75381 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 5/20 | 0.34 |
| ▸ | MC4R | P32245 | 2/20 | 0.33 |
| ▸ | MC1R | Q01726 | 2/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484586 | 1.00 | P2RX7 (0.37) | P2RX7PEX14CCR4MC4RMC1R | |
| SCHEMBL5736469 | 0.93 | CCR4 (0.41) | P2RX7PEX14CCR4MC4RMC1R | |
| SCHEMBL5736465 | 0.93 | CCR4 (0.41) | P2RX7PEX14CCR4MC4RMC1R | |
| SCHEMBL4936450 | 0.86 | P2RX7 (0.40) | P2RX7PEX14CCR4MC4RMC1R | |
| SCHEMBL4936458 | 0.86 | P2RX7 (0.40) | P2RX7PEX14CCR4MC4RMC1R | |
| SCHEMBL4945653 | 0.86 | P2RX7 (0.42) | P2RX7PEX14CCR4MC4RMC1R | |
| SCHEMBL4945655 | 0.86 | P2RX7 (0.42) | P2RX7PEX14CCR4MC4RMC1R | |
| SCHEMBL4944148 | 0.79 | GLP1R (0.39) | P2RX7PEX14CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4944155 | 0.79 | GLP1R (0.39) | P2RX7PEX14CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5743398 | 0.78 | CCR4 (0.41) | P2RX7PEX14CCR4EPHX2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211601-B2 | Pharmaceutically active pyrrolidine derivatives | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-05-01 | — | — | US | disclosed |