Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 10/20 | 0.41 |
| ▸ | PEX14 | O75381 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | CLPP | Q16740 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215356 | 0.87 | PEX14 (0.41) | CCR4PEX14P2RX7EPHX2CLPP | |
| SCHEMBL5736465 | 0.84 | CCR4 (0.41) | CCR4PEX14P2RX7EPHX2F12 | |
| SCHEMBL5736469 | 0.84 | CCR4 (0.41) | CCR4PEX14P2RX7EPHX2F12 | |
| SCHEMBL5484587 | 0.78 | P2RX7 (0.37) | CCR4PEX14P2RX7EPHX2DRD2 | |
| SCHEMBL5484586 | 0.78 | P2RX7 (0.37) | CCR4PEX14P2RX7EPHX2DRD2 | |
| SCHEMBL4945653 | 0.72 | P2RX7 (0.42) | CCR4PEX14P2RX7EPHX2 | |
| SCHEMBL4945655 | 0.72 | P2RX7 (0.42) | CCR4PEX14P2RX7EPHX2 | |
| SCHEMBL4936450 | 0.72 | P2RX7 (0.40) | CCR4PEX14P2RX7EPHX2 | |
| SCHEMBL4936458 | 0.72 | P2RX7 (0.40) | CCR4PEX14P2RX7EPHX2 | |
| SCHEMBL4936215 | 0.68 | P2RX7 (0.41) | CCR4PEX14P2RX7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | disclosed |