Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413664 | 0.79 | TAAR1 (0.52) | ALDH1A1TSHRAOC3 | |
| SCHEMBL5490217 | 0.79 | IDO1 (0.38) | KDM4ETP53TYRHPGDHTT | |
| SCHEMBL24362693 | 0.77 | HDAC4 (0.45) | HDAC4HDAC8HDAC2KDM4EMDM4 | |
| SCHEMBL4451930 | 0.76 | HDAC4 (0.33) | HDAC4HDAC8HDAC2HPGDSMN1; SMN2 | |
| SCHEMBL4451929 | 0.76 | HDAC4 (0.33) | HDAC4HDAC8HDAC2HPGDSMN1; SMN2 | |
| SCHEMBL374780 | 0.76 | HDAC4 (0.56) | HDAC4HDAC8HDAC2KDM4EMDM4 | |
| SCHEMBL7778471 | 0.75 | HDAC4 (0.56) | HDAC4HDAC8HDAC2KDM4EMDM4 | |
| SCHEMBL2925065 | 0.74 | HDAC4 (0.42) | HDAC4HDAC8HDAC2KDM4EMDM4 | |
| SCHEMBL2925067 | 0.74 | HDAC4 (0.42) | HDAC4HDAC8HDAC2KDM4EMDM4 | |
| SCHEMBL25094316 | 0.74 | HDAC4 (0.47) | HDAC4HDAC8HDAC2KDM4EMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |