Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451930 | 1.00 | HDAC4 (0.33) | HDAC4HDAC2HDAC8CNR2HPGD | |
| SCHEMBL4440892 | 0.83 | HDAC4 (0.32) | HDAC4HDAC2HDAC8 | |
| SCHEMBL5598759 | 0.81 | — | — | |
| SCHEMBL11518269 | 0.80 | HDAC4 (0.51) | HDAC4HDAC2HDAC8CNR2HPGD | |
| SCHEMBL4442160 | 0.80 | HDAC4 (0.33) | HDAC4HDAC2HDAC8HPGDATM | |
| SCHEMBL4442162 | 0.80 | HDAC4 (0.33) | HDAC4HDAC2HDAC8HPGDATM | |
| SCHEMBL10447240 | 0.79 | TAAR1 (0.50) | HDAC4HDAC2HDAC8CNR2HPGD | |
| SCHEMBL5485069 | 0.76 | HDAC4 (0.39) | HDAC4HDAC2HDAC8HPGDSMN1; SMN2 | |
| SCHEMBL14051358 | 0.76 | TYR (0.46) | HDAC4HDAC2HDAC8CNR2HPGD | |
| SCHEMBL20931111 | 0.73 | CNR2 (0.37) | HDAC4HDAC2HDAC8CNR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789423-B1 | SILANE COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND RUBBER COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-04-13 | — | — | EP | disclosed |
| US-7531588-B2 | Silane compositions, processes for their preparation and rubber compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-05-12 | — | — | US | disclosed |
| US-20060281841-A1 | Silane compositions, processes for their preparation and rubber compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-12-14 | — | — | US | disclosed |
| US-20060025506-A1 | Silane compositions, processes for their preparation and rubber compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-02-02 | — | — | US | disclosed |