Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.70 |
| ▸ | RARA | P10276 | 2/20 | 0.64 |
| ▸ | RARB | P10826 | 2/20 | 0.64 |
| ▸ | RARG | P13631 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 13/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 12/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20655868 | 0.92 | CYP3A4 (0.65) | CYP3A4CYP26A1RARARARBRARG | |
| SCHEMBL17885757 | 0.87 | CYP3A4 (0.71) | CYP3A4CYP26A1RARARARBRARG | |
| SCHEMBL6665694 | 0.86 | CYP3A4 (0.70) | CYP3A4CYP26A1RARARARBRARG | |
| SCHEMBL19342896 | 0.86 | CYP3A4 (0.57) | CYP3A4CYP26A1RARARARBRARG | |
| SCHEMBL180442 | 0.84 | CYP3A4 (0.70) | CYP3A4CYP26A1RARARARBRARG | |
| SCHEMBL860637 | 0.83 | CYP3A4 (0.69) | CYP3A4CYP26A1RARARARBRARG | |
| SCHEMBL30374281 | 0.83 | CYP3A4 (0.69) | CYP3A4CYP26A1RARARARBRARG | |
| SCHEMBL19342919 | 0.83 | CYP3A4 (0.49) | CYP3A4CYP26A1RARARARBRARG | |
| SCHEMBL14330777 | 0.82 | CYP3A4 (0.84) | CYP3A4CYP26A1RARARARBRARG | |
| SCHEMBL8765958 | 0.82 | CYP3A4 (0.68) | CYP3A4CYP26A1RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688667-B2 | Tazarotene with low dimer impurity for treating acne or psoriasis | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2017-06-27 | — | — | US | disclosed |
| US-9688667-B2 | Tazarotene with low dimer impurity for treating acne or psoriasis | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2017-06-27 | — | — | US | disclosed |
| US-20160304503-A1 | TAZAROTENE WITH LOW DIMER IMPURITY FOR TREATING ACNE OR PSORIASIS | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2016-10-20 | — | — | US | disclosed |
| US-20160304503-A1 | TAZAROTENE WITH LOW DIMER IMPURITY FOR TREATING ACNE OR PSORIASIS | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2016-10-20 | — | — | US | disclosed |
| WO-2015107542-A2 | TAZAROTENE WITH LOW DIMER IMPURITY FOR TREATING ACNE OR PSORIASIS | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2015-07-23 | — | — | WO | disclosed |
| US-20070238881-A1 | Process for the preparation of tazarotene intermediates and use thereof for the preparation of tazarotene | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-10-11 | — | — | US | disclosed |
| US-20070238881-A1 | Process for the preparation of tazarotene intermediates and use thereof for the preparation of tazarotene | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238881-A1 | Process for the preparation of tazarotene intermediates and use thereof for the preparation of tazarotene | NAMPT, NAPRT, NNT | CYP3A4 125/4885CYP26A1 289/4885RARA 1989/4885 |
| US-20160304503-A1 | TAZAROTENE WITH LOW DIMER IMPURITY FOR TREATING ACNE OR PSORIASIS | PPIA, CUTA, TFPI | CYP3A4 563/4885CYP26A1 926/4885RARA 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.