Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479537 | 1.00 | ATM (0.41) | ATMAKT1CA12CA1CA7 | |
| SCHEMBL7849694 | 0.74 | MAPT (0.39) | ATMAKT1CA12CA1CA7 | |
| SCHEMBL3375626 | 0.72 | MAPT (0.42) | ATMAKT1CA12CA1CA7 | |
| SCHEMBL27791882 | 0.72 | KMT2A (0.45) | ATMAKT1CA12CA1CA7 | |
| SCHEMBL3009386 | 0.70 | CYP1A2 (0.43) | ATMAKT1CA12CA1CA7 | |
| SCHEMBL29770797 | 0.70 | CA12 (0.44) | ATMAKT1CA12CA1CA7 | |
| SCHEMBL27437344 | 0.70 | AKT1 (0.43) | ATMAKT1CA12CA1CA7 | |
| SCHEMBL3592587 | 0.70 | CA12 (0.48) | ATMAKT1CA12CA1CA7 | |
| SCHEMBL3592585 | 0.70 | CA12 (0.48) | ATMAKT1CA12CA1CA7 | |
| SCHEMBL2067964 | 0.70 | IDO1 (0.43) | ATMAKT1CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015439-B1 | PRENYL TRANSFERASE INHIBITORS | SOD CONSEILS RECH APPLIC (FR) | 2007-04-11 | — | — | EP | disclosed |
| EP-1676855-A2 | Prenyl transferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (S.C.R.A.S.) (FR) | 2006-07-05 | — | — | EP | disclosed |
| EP-1015439-A4 | PRENYL TRANSFERASE INHIBITORS | BIOMEASURE INC (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-1015439-A1 | PRENYL TRANSFERASE INHIBITORS | BIOMEASURE, INC. (US) | 2000-07-05 | — | — | EP | disclosed |
| US-5767274-A | TREATING TUMORS OR RESTENOSIS | BIOMEASURE, INCORPORATED (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1998000411-A1 | PRENYL TRANSFERASE INHIBITORS | BIOMEASURE INCORPORATED (US) | 1998-01-08 | — | — | WO | disclosed |
| US-5352705-A | Dipeptide-based amide compounds; anticarcinogenic agents | MERCK & CO., INC. (US) | 1994-10-04 | — | — | US | disclosed |