Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375626 | 0.81 | MAPT (0.42) | MAPTCA12CA1CA7CA14 | |
| SCHEMBL2979888 | 0.77 | MAPT (0.47) | MAPTCA12CA1CA7CA14 | |
| SCHEMBL5479537 | 0.74 | ATM (0.41) | MAPTCA12CA1CA7CA14 | |
| SCHEMBL5485091 | 0.74 | ATM (0.41) | MAPTCA12CA1CA7CA14 | |
| SCHEMBL8961238 | 0.73 | KMT2A (0.40) | CYP2C19MEN1GAAKMT2ACTSS | |
| SCHEMBL8741676 | 0.72 | ACE (0.44) | CYP2C19KMT2AKCNA3 | |
| SCHEMBL27791882 | 0.72 | KMT2A (0.45) | MAPTCA12CA1CA7CA14 | |
| SCHEMBL3018218 | 0.72 | CA12 (0.43) | CA12CA1CA7CA14ATM | |
| SCHEMBL6062430 | 0.71 | CA12 (0.44) | MAPTCA12CA1CA7CA14 | |
| SCHEMBL6062427 | 0.71 | CA12 (0.44) | MAPTCA12CA1CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015439-A4 | PRENYL TRANSFERASE INHIBITORS | BIOMEASURE INC (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-1015439-A1 | PRENYL TRANSFERASE INHIBITORS | BIOMEASURE, INC. (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998000411-A1 | PRENYL TRANSFERASE INHIBITORS | BIOMEASURE INCORPORATED (US) | 1998-01-08 | — | — | WO | disclosed |
| EP-0703905-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1996-04-03 | — | — | EP | disclosed |