Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 2/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355735 | 0.86 | — | — | |
| SCHEMBL1535183 | 0.86 | TSHR (0.39) | TSHRHIF1AFAAHTRPV1 | |
| SCHEMBL1535213 | 0.79 | HIF1A (0.39) | TSHRHIF1AFAAHTRPV1 | |
| SCHEMBL10397718 | 0.76 | TSHR (0.67) | TSHRFAAHTRPV1HMGCRPTPN7 | |
| SCHEMBL10397035 | 0.76 | TSHR (0.67) | TSHRFAAHTRPV1HMGCRPTPN7 | |
| SCHEMBL10398057 | 0.76 | TSHR (0.67) | TSHRFAAHTRPV1HMGCRPTPN7 | |
| SCHEMBL10398208 | 0.76 | TSHR (0.67) | TSHRFAAHTRPV1HMGCRPTPN7 | |
| SCHEMBL10397635 | 0.76 | TSHR (0.67) | TSHRFAAHTRPV1HMGCRPTPN7 | |
| SCHEMBL10398522 | 0.76 | TSHR (0.67) | TSHRFAAHTRPV1HMGCRPTPN7 | |
| SCHEMBL10398213 | 0.76 | TSHR (0.67) | TSHRFAAHTRPV1HMGCRPTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183432-B2 | Synthesis of ynamides | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183432-B2 | Synthesis of ynamides | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183432-B2 | Synthesis of ynamides | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| US-20050272954-A1 | Synthesis of ynamides | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272954-A1 | Synthesis of ynamides | DDOST, GYPA, ADH1C | TSHR 4471/4885HIF1A 2796/4885FAAH 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.