⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485121 | 0.86 | TSHR (0.35) | — | |
| SCHEMBL1535190 | 0.84 | ALDH1A1 (0.33) | — | |
| SCHEMBL1354903 | 0.80 | TRPA1 (0.32) | — | |
| SCHEMBL1354901 | 0.80 | TRPA1 (0.32) | — | |
| SCHEMBL12133294 | 0.75 | — | — | |
| SCHEMBL1355531 | 0.74 | — | — | |
| SCHEMBL1356531 | 0.74 | GABRR1 (0.32) | — | |
| SCHEMBL1356530 | 0.74 | GABRR1 (0.32) | — | |
| SCHEMBL17818231 | 0.72 | — | — | |
| SCHEMBL1535213 | 0.71 | HIF1A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2543262-B1 | Flavor-enhancing amide compounds | INT FLAVORS & FRAGRANCES INC (US) | 2015-02-18 | — | — | EP | disclosed |
| US-20130011345-A1 | FLAVOR-ENHANCING AMIDE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2013-01-10 | — | — | US | disclosed |
| US-20130011345-A1 | FLAVOR-ENHANCING AMIDE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2013-01-10 | — | — | US | disclosed |
| EP-2543262-A1 | Flavor-enhancing amide compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-01-09 | — | — | EP | disclosed |
| US-20110280812-A1 | FLAVOR-ENHANCING AMIDE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-11-17 | — | — | US | disclosed |
| US-20110280812-A1 | FLAVOR-ENHANCING AMIDE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-11-17 | — | — | US | disclosed |
| EP-2386212-A2 | Flavor-enhancing amide compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-11-16 | — | — | EP | disclosed |