SCHEMBL54852

SCHEMBL54852

C[C@H](O)CCCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50388 1.00
SCHEMBL2380939 1.00
1,4-Butanediol SCHEMBL8983355 0.97 TDP1 (0.44)
SCHEMBL27787445 0.97
SCHEMBL28299896 0.97
1,5-Pentanediol SCHEMBL6905317 0.94 ALDH1A1 (0.43)
1,6-Hexanediol SCHEMBL7211787 0.94 ALDH1A1 (0.43)
SCHEMBL17686274 0.91 TDP1 (0.40)
SCHEMBL41064 0.90
SCHEMBL3401418 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6228293-A None JP disclosed
CN-115490708-B Sulfonamide macrocyclic derivative, preparation method and application thereof 苏州亚盛药业有限公司 2025-01-24 CN disclosed
CN-115490708-A Sulfonamide macrocyclic derivatives, and preparation method and application thereof 苏州亚盛药业有限公司 2022-12-20 CN disclosed
EP-2096165-B1 NOVEL ALCOHOL DEHYDROGENASE, GENE FOR THE ALCOHOL DEHYDROGENASE, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOL BY USING THEM KANEKA CORP (JP) 2016-08-24 EP disclosed
US-8129163-B2 Gene suitable for alcohol dehydrogenase, vector and transformant KANEKA CORPORATION (JP) 2012-03-06 US disclosed
US-20110287494-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINE DERIVATIVE DAICEL CHEMICAL INDUSTRIES LTD (JP) 2011-11-24 US disclosed
EP-1422255-B1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY NIPPON OIL CORP (JP) 2011-09-28 EP disclosed
EP-2330190-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINE DERIVATIVE Daicel Chemical Industries, Ltd. (JP) 2011-06-08 EP disclosed
US-7807426-B2 Processes for producing optically active 1-substituted 2-methylpyrrolidine KANEKA CORPORATION (JP) 2010-10-05 US disclosed
US-20100035317-A1 NOVEL ALCOHOL DEHYDROGENASE, GENE FOR THE ALCOHOL DEHYDROGENASE, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOL BY USING THEM KANEKA CORPORATION (JP) 2010-02-11 US disclosed
US-20070292926-A1 Processes for Producing Optically Active 1-Substituted 2-Methylpyrrolidine and Intermediate Therefor KANEKA CORPORATION (JP) 2007-12-20 US disclosed
US-7230135-B2 Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts WARNER LAMBERT COMPANY LLC (US) 2007-06-12 US disclosed
EP-1715054-A1 PROCESSES FOR PRODUCING OPTICALLY ACTIVE 1-SUBSTITUTED 2-METHYLPYRROLIDINE AND INTERMEDIATE THEREFOR KANEKA CORPORATION (JP) 2006-10-25 EP disclosed
US-6967196-B1 Sulfonamide compounds and uses thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2005-11-22 US disclosed
US-6894141-B2 Main chain type liquid crystalline polyester, liquid crystalline composition, method for producing liquid crystal film and optical film, and display having optical film NIPPON OIL CORPORATION (JP) 2005-05-17 US disclosed
US-20040171788-A1 Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display NOBLE VENTURE FINANCE I LIMITED (GB) 2004-09-02 US disclosed
EP-1422255-A1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY Nippon Oil Corporation (JP) 2004-05-26 EP disclosed
EP-1159263-A1 NOVEL SULFONAMIDE COMPOUNDS AND USES THEREOF Merck & Co., Inc. (US) 2001-12-05 EP disclosed
WO-2000050391-A1 NOVEL SULFONAMIDE COMPOUNDS AND USES THEREOF MERCK & CO., INC. (US) 2000-08-31 WO disclosed
JP-H06228293-A LIQUID CRYSTALLINE POLYESTER NIPPON OIL CO LTD 1994-08-16 JP disclosed