Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.59 |
| ▸ | CTSL | P07711 | 8/20 | 0.59 |
| ▸ | CTSS | P25774 | 8/20 | 0.59 |
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188272 | 0.90 | CTSK (0.57) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5528745 | 0.83 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5566410 | 0.79 | CTSK (0.46) | CTSKCTSLCTSS | |
| SCHEMBL4450584 | 0.78 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5315258 | 0.77 | GRIN2B (0.56) | — | |
| SCHEMBL10154348 | 0.76 | LCK (0.54) | — | |
| SCHEMBL4691169 | 0.76 | CTSK (0.90) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4691173 | 0.76 | CTSK (0.90) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4691167 | 0.76 | CTSK (0.90) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5489887 | 0.76 | RAB9A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869026-A1 | NOVEL COMPOUNDS | SmithKline Beecham Corporation (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006105475-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-05 | — | — | WO | disclosed |