SCHEMBL5485264

SCHEMBL5485264

CCCCCN(C(=O)OCC)c1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
PABPC1 P11940 3/20 0.47
ALDH1A1 P00352 6/20 0.46
MAPT P10636 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
LMNA P02545 2/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
NSD2 O96028 1/20 0.46
EGFR P00533 1/20 0.46
TP53 P04637 2/20 0.45
ELANE P08246 2/20 0.42
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
PAX8 Q06710 2/20 0.40
KEAP1 Q14145 1/20 0.40
JAK2 O60674 1/20 0.40
APAF1 O14727 1/20 0.39
MITF O75030 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509247 0.79 ALDH1A1 (0.49) MEN1KMT2APABPC1ALDH1A1MAPT
SCHEMBL8159209 0.78 MEN1 (0.66) MEN1KMT2APABPC1ALDH1A1MAPT
SCHEMBL11868134 0.77 PABPC1 (0.64) MEN1KMT2APABPC1ALDH1A1MAPT
SCHEMBL11334744 0.77 PABPC1 (0.64) MEN1KMT2APABPC1ALDH1A1MAPT
SCHEMBL10697720 0.77 PABPC1 (0.64) MEN1KMT2APABPC1ALDH1A1MAPT
SCHEMBL11865205 0.77 PABPC1 (0.64) MEN1KMT2APABPC1ALDH1A1MAPT
SCHEMBL996368 0.75 ALDH1A1 (0.45) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL8393246 0.74 NPC1 (0.64) MEN1KMT2AALDH1A1MAPTTP53
SCHEMBL2328263 0.74 MEN1 (0.68) MEN1KMT2APABPC1ALDH1A1MAPT
SCHEMBL28825361 0.73 ALDH1A1 (0.46) MEN1KMT2AALDH1A1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070149699-A1 Contact lens material MENICON CO., LTD. (JP) 2007-06-28 US disclosed