SCHEMBL5485410

SCHEMBL5485410

CCc1ccccc1C=C(C)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.55
APEX1 P27695 8/20 0.42
CYP2C9 P11712 1/20 0.40
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
NR4A2 P43354 1/20 0.39
RXRG P48443 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HTT P42858 1/20 0.39
TRPA1 O75762 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5863271 0.88 AKR1C3 (0.50) AKR1C3APEX1CYP2C9RXRARXRB
SCHEMBL5863276 0.88 AKR1C3 (0.50) AKR1C3APEX1CYP2C9RXRARXRB
SCHEMBL3893886 0.84 AKR1C3 (0.68) AKR1C3APEX1CYP2C9RXRARXRB
SCHEMBL31666241 0.84 AKR1C3 (0.68) AKR1C3APEX1CYP2C9RXRARXRB
SCHEMBL8746671 0.84 AKR1C3 (0.68) AKR1C3APEX1CYP2C9RXRARXRB
SCHEMBL8515208 0.83 TP53 (0.44) AKR1C3CYP2C9KDM4EHTT
SCHEMBL2120927 0.83 AKR1C3 (0.49) AKR1C3APEX1CYP2C9KDM4EHTT
SCHEMBL14673256 0.82 BID (0.48) AKR1C3KDM4E
SCHEMBL27960141 0.80 ELANE (0.39) AKR1C3KDM4ETRPA1
SCHEMBL7766698 0.79 AKR1C3 (0.57) AKR1C3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101180086-A Sustained release implants for subretinal delivery SURMODICS INC (US) 2008-05-14 CN claimed
EP-3517571-A1 (METH)ACRYLIC COPOLYMER, RESIN COMPOSITION, MOLDED BODY OF SAME, AND METHOD FOR PRODUCING MOLDED BODY Mitsubishi Gas Chemical Company, Inc. (JP) 2019-07-31 EP disclosed
CN-101180086-A Sustained release implants for subretinal delivery SURMODICS INC (US) 2008-05-14 CN disclosed
US-20070172772-A1 Microlens OMRON CORPORATION (JP) 2007-07-26 US disclosed
CN-1950116-A Composition and method for preparing biocompatible surfaces SURMODICS INC (US) 2007-04-18 CN disclosed
EP-0797459-B1 COATING PROCESS MEDICARB AB (SE) 2003-05-14 EP disclosed
US-5885647-A Coating process MEDICARB AB (SE) 1999-03-23 US disclosed
EP-0797459-A1 COATING PROCESS MEDICARB AB (SE) 1997-10-01 EP disclosed
WO-1996018423-A1 COATING PROCESS MEDICARB AB (SE) 1996-06-20 WO disclosed
EP-0590723-A1 Block copolymers containing polyaromatic(alkyl)methacrylates and their blends with polycarbonates ENICHEM S.p.A. (IT) 1994-04-06 EP disclosed
US-5284916-A Transparent melt processable compatible thermoplastic blends ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1994-02-08 US disclosed