SCHEMBL5863271

SCHEMBL5863271

CCCc1ccccc1/C=C(\C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.50
APEX1 P27695 8/20 0.40
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38
CYP2C9 P11712 1/20 0.37
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
NR4A2 P43354 1/20 0.36
RXRG P48443 1/20 0.36
KDM4E B2RXH2 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
PRKCI P41743 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5863276 1.00 AKR1C3 (0.50) AKR1C3APEX1LTB4RLTB4R2CYP2C9
SCHEMBL5485410 0.88 AKR1C3 (0.55) AKR1C3APEX1CYP2C9RXRARXRB
SCHEMBL14673256 0.88 BID (0.48) AKR1C3KDM4EPPARGPPARA
SCHEMBL5507396 0.81 AKR1C3 (0.45) AKR1C3APEX1LTB4RLTB4R2CYP2C9
SCHEMBL3893886 0.80 AKR1C3 (0.68) AKR1C3APEX1CYP2C9RXRARXRB
SCHEMBL31666241 0.80 AKR1C3 (0.68) AKR1C3APEX1CYP2C9RXRARXRB
SCHEMBL8746671 0.80 AKR1C3 (0.68) AKR1C3APEX1CYP2C9RXRARXRB
SCHEMBL2120927 0.79 AKR1C3 (0.49) AKR1C3APEX1CYP2C9KDM4EHTT
SCHEMBL6547041 0.78 BRD4 (0.36) CYP2C9PPARGPPARAHTT
SCHEMBL28329262 0.78 ALDH1A1 (0.47) PPARGPPARAPRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7022455-B2 Photoacid-labile polymers and photoresists comprising same SHIPLEY COMPANY, L.L.C. (US) 2006-04-04 US disclosed
US-20030232274-A1 Photoacid-labile polymers and photoresists comprising same SHIPLEY COMPANY, L.L.C. 2003-12-18 US disclosed