Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987968 | 0.84 | HDAC8 (1.00) | HDAC8USP2NNMTLMNAACHE | |
| SCHEMBL8731836 | 0.84 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL5480758 | 0.83 | HDAC8 (0.69) | HDAC8USP2ACHE | |
| Iodide SCHEMBL8404077 | 0.82 | HDAC8 (0.96) | HDAC8USP2NNMTLMNAACHE | |
| SCHEMBL5483989 | 0.81 | HDAC8 (0.64) | HDAC8ACHEBCHECA12CA1 | |
| SCHEMBL11689059 | 0.76 | USP2 (0.42) | HDAC8USP2NNMTLMNAACHE | |
| SCHEMBL8987989 | 0.75 | HDAC8 (0.73) | HDAC8USP2NNMTLMNATSHR | |
| SCHEMBL20544696 | 0.75 | USP2 (0.41) | HDAC8USP2NNMTLMNAACHE | |
| SCHEMBL11692088 | 0.75 | HDAC8 (0.68) | HDAC8USP2NNMTLMNAACHE | |
| SCHEMBL20544622 | 0.72 | LMNA (0.41) | HDAC8USP2NNMTLMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854786-A1 | Ionic liquids and their use in extraction processes | BP p.l.c. (GB) | 2007-11-14 | — | — | EP | claimed |
| EP-1854786-A1 | Ionic liquids and their use in extraction processes | BP p.l.c. (GB) | 2007-11-14 | — | — | EP | disclosed |