Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490122 | 0.86 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL6274690 | 0.80 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL277923 | 0.80 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL4563557 | 0.80 | TSHR (0.35) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11252991 | 0.80 | TSHR (0.35) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL692578 | 0.78 | TSHR (0.38) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27991172 | 0.78 | TSHR (0.35) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27494684 | 0.78 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL147629 | 0.78 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL18427851 | 0.77 | THRB (0.39) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060994-A1 | Blood flow diverters for the treatment of intracranial aneurysms | GOBRAN RIAD H | 2007-03-15 | — | — | US | claimed |
| US-20050283220-A1 | Blood flow diverters for the treatment of intracranial aneurysms | GOBRAN RIAD H | 2005-12-22 | — | — | US | claimed |
| JP-60168712-A | — | — | None | — | — | JP | disclosed |
| US-5250645-A | Methoxypolyalkoxyethyl methacrylate or acrylate, an initiator, polymerization accelerator and water | RHONE-POULENC CHIMIE (FR) | 1993-10-05 | — | — | US | disclosed |
| JP-S60168712-A | AQUEOUS TWO-LAYER POLYMER EMULSION AND ITS PRODUCTION | NITTO ELECTRIC IND CO LTD | 1985-09-02 | — | — | JP | disclosed |