Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SOD1 | P00441 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19384428 | 0.85 | LMNA (0.61) | MAOBALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL19384259 | 0.85 | LMNA (0.61) | MAOBALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL19384288 | 0.85 | LMNA (0.61) | MAOBALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL3229817 | 0.84 | TSHR (0.66) | MAOBALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL3229807 | 0.84 | TSHR (0.66) | MAOBALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL772753 | 0.82 | KMT2A (0.51) | MAOBALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL14027336 | 0.82 | ALDH1A1 (0.54) | MAOBALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL8179344 | 0.82 | KMT2A (0.51) | MAOBALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL23363494 | 0.81 | MAOB (0.47) | MAOBALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL29934083 | 0.81 | MAOB (0.47) | MAOBALDH1A1KMT2AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142929-A2 | NOVEL PDE4 INHIBITORS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-12-13 | — | — | WO | disclosed |