Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763666 | 0.81 | ADAMTS5 (0.61) | L3MBTL1MAPTPOLBCCKBRTP53 | |
| SCHEMBL2765949 | 0.81 | ADAMTS5 (0.61) | L3MBTL1MAPTPOLBCCKBRTP53 | |
| SCHEMBL13398362 | 0.81 | ADAMTS5 (0.61) | L3MBTL1MAPTPOLBCCKBRTP53 | |
| SCHEMBL15882461 | 0.81 | L3MBTL1 (0.61) | L3MBTL1MAPTPOLBCCKBRTP53 | |
| SCHEMBL2787143 | 0.80 | MAPT (0.48) | L3MBTL1MAPTPOLBCCKBRTP53 | |
| SCHEMBL14208625 | 0.80 | ADAMTS5 (0.60) | L3MBTL1MAPTPOLBCCKBRTP53 | |
| SCHEMBL2764939 | 0.80 | ADAMTS5 (0.60) | L3MBTL1MAPTPOLBCCKBRTP53 | |
| SCHEMBL14208349 | 0.80 | ADAMTS5 (0.60) | L3MBTL1MAPTPOLBCCKBRTP53 | |
| SCHEMBL2764820 | 0.80 | ADAMTS5 (0.45) | L3MBTL1MAPTPOLBCCKBRTP53 | |
| SCHEMBL2764817 | 0.80 | ADAMTS5 (0.45) | L3MBTL1MAPTPOLBCCKBRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007516982-A | — | — | 2007-06-28 | — | — | JP | claimed |
| EP-1694410-A2 | CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2006-08-30 | — | — | EP | claimed |
| WO-2005058884-A2 | CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2005-06-30 | — | — | WO | claimed |
| EP-1694410-A2 | CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058884-A2 | CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2005-06-30 | — | — | WO | disclosed |