SCHEMBL5486033

SCHEMBL5486033

CN(C)CCCNc1nc(Cl)nc(Cl)n1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.51
LMNA P02545 1/20 0.45
KDM1A O60341 1/20 0.43
RCOR1 Q9UKL0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24622129 0.89 KMT2A (0.51) KMT2ALMNA
SCHEMBL11783695 0.86 KDM1A (0.49) KMT2AKDM1ARCOR1
SCHEMBL25809403 0.84 KMT2A (0.51) KMT2ALMNA
SCHEMBL25809366 0.81 KMT2A (0.45) KMT2ALMNA
SCHEMBL13558679 0.81 KMT2A (0.53) KMT2ALMNA
SCHEMBL20053796 0.81 KMT2A (0.58) KMT2ALMNA
SCHEMBL140123 0.79 KMT2A (0.61) KMT2ALMNA
SCHEMBL25166617 0.79 KCNH2 (0.41) KDM1ARCOR1
SCHEMBL4874795 0.78 KMT2A (0.57) KMT2ALMNA
SCHEMBL9357110 0.78 KMT2A (0.61) KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189266-B2 Dyeing composition for human keratinous fibres with direct dyes and dicationic compounds L'OREAL, S.A. (FR) 2007-03-13 US claimed
US-20040237213-A1 Dyeing composition for human keratinous fibres with direct dyes and dicationic compounds L'OREAL S.A. (FR) 2004-12-02 US claimed
EP-1399115-A1 DYEING COMPOSITION FOR HUMAN KERATINOUS FIBRES WITH DIRECT DYES AND DICATIONIC COMPOUNDS L'OREAL (FR) 2004-03-24 EP claimed
WO-2002100367-A1 DYEING COMPOSITION FOR HUMAN KERATINOUS FIBRES WITH DIRECT DYES AND DICATIONIC COMPOUNDS L'OREAL (FR) 2002-12-19 WO claimed
EP-0318294-B1 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS (JP) 1994-12-28 EP claimed
EP-0318294-A2 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS CO., LTD (JP) 1989-05-31 EP claimed
US-11702712-B2 Cationic cyanuric chloride derivative tanning agent and preparation method thereof SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2023-07-18 US disclosed
US-11702712-B2 Cationic cyanuric chloride derivative tanning agent and preparation method thereof SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2023-07-18 US disclosed
US-20220220569-A1 CATIONIC CYANURIC CHLORIDE DERIVATIVE TANNING AGENT AND PREPARATION METHOD THEREOF SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2022-07-14 US disclosed
US-7189266-B2 Dyeing composition for human keratinous fibres with direct dyes and dicationic compounds L'OREAL, S.A. (FR) 2007-03-13 US disclosed
US-20040237213-A1 Dyeing composition for human keratinous fibres with direct dyes and dicationic compounds L'OREAL S.A. (FR) 2004-12-02 US disclosed
EP-1399115-A1 DYEING COMPOSITION FOR HUMAN KERATINOUS FIBRES WITH DIRECT DYES AND DICATIONIC COMPOUNDS L'OREAL (FR) 2004-03-24 EP disclosed
WO-2002100367-A1 DYEING COMPOSITION FOR HUMAN KERATINOUS FIBRES WITH DIRECT DYES AND DICATIONIC COMPOUNDS L'OREAL (FR) 2002-12-19 WO disclosed
EP-0318294-B1 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS (JP) 1994-12-28 EP disclosed
US-5125930-A Polymeric cationic dyes including a quaternized pyridinium group NIPPON CHEMICAL WORKS CO., LTD. (JP) 1992-06-30 US disclosed
EP-0318294-A2 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS CO., LTD (JP) 1989-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220220569-A1 CATIONIC CYANURIC CHLORIDE DERIVATIVE TANNING AGENT AND PREPARATION METHOD THEREOF C9, PROC, TYR KMT2A 3823/4885LMNA 2491/4885KDM1A 1127/4885
US-20040237213-A1 Dyeing composition for human keratinous fibres with direct dyes and dicationic compounds KRT18, DSG1, DSC1 KMT2A 1904/4885LMNA 315/4885KDM1A 995/4885
US-11702712-B2 Cationic cyanuric chloride derivative tanning agent and preparation method thereof C9, PROC, TYR KMT2A 3823/4885LMNA 2491/4885KDM1A 1127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.