Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469176 | 1.00 | HTR1A (0.48) | HTR1AKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL5475350 | 1.00 | HTR1A (0.48) | HTR1AKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL5472134 | 0.89 | HTR1A (0.47) | HTR1AKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL5858360 | 0.89 | HTR1A (0.53) | HTR1AKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL5859373 | 0.89 | HTR1A (0.53) | HTR1AKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL5858732 | 0.89 | HTR1A (0.53) | HTR1AKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL5858801 | 0.89 | HTR1A (0.53) | HTR1AKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL5858707 | 0.89 | HTR1A (0.53) | HTR1AKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL5472136 | 0.87 | HTR1A (0.47) | HTR1AKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL5473762 | 0.87 | HTR1A (0.47) | HTR1AKDM4EALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270436-A1 | NOVEL AMINO- AND IMINO-ALKYLPIPERAZINES | RECORDATI IRELAND LIMITED (IE) | 2007-11-22 | — | — | US | claimed |
| US-20070270436-A1 | NOVEL AMINO- AND IMINO-ALKYLPIPERAZINES | RECORDATI IRELAND LIMITED (IE) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270436-A1 | NOVEL AMINO- AND IMINO-ALKYLPIPERAZINES | HTR5A, HTR1A, HTR2C | HTR1A 2/4885KDM4E 4003/4885ALDH1A1 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.