SCHEMBL548616

SCHEMBL548616

O=C1NC2C=CC1C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8223422 1.00
SCHEMBL5397907 0.70 ALDH1A1 (0.36)
SCHEMBL19250783 0.65
SCHEMBL9587213 0.54 TDP1 (0.35)
SCHEMBL12154365 0.54
SCHEMBL1411619 0.54
SCHEMBL6202105 0.54
SCHEMBL2979101 0.53
Noreximide SCHEMBL14536593 0.51 ALDH1A1 (0.48)
Noreximide SCHEMBL339739 0.51 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 762 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263428-A Treatment method of 2-azabicyclo [2.2.1] hept-5-en-3-one production wastewater 河北诚信集团有限公司 2023-12-22 CN claimed
US-10385006-B2 Process for the preparation of amino alcohol derivatives or salts thereof GRANULES INDIA LIMITED (IN) 2019-08-20 US claimed
US-20170233329-A1 PROCESS FOR THE PREPARATION OF AMINO ALCOHOL DERIVATIVES OR SALTS THEREOF GRANULES INDIA LTD (IN) 2017-08-17 US claimed
WO-2016067182-A2 PROCESS FOR THE PREPARATION OF AMINO ALCOHOL DERIVATIVES OR SALTS THEREOF GRANULES INDIA LIMITED (IN) 2016-05-06 WO claimed
US-20100163070-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE L'OREAL S.A. (FR) 2010-07-01 US claimed
EP-0925361-B1 MICROORGANISM, LACTAMASE ENZYME OBTAINED THEREFROM, AND THEIR USE CHIROTECH TECHNOLOGY LTD (GB) 2009-12-09 EP claimed
EP-2029235-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AMIDE L'Oréal (FR) 2009-03-04 EP claimed
EP-1982985-A2 Method for manufacturing a purine derivative Lonza AG (CH) 2008-10-22 EP claimed
EP-1508565-B1 Process for the preparation of optically active aminoalcohols LONZA AG (CH) 2008-08-13 EP claimed
WO-2007135296-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AMIDE L'OREAL (FR) 2007-11-29 WO claimed
EP-0508352-B1 Process for the preparation of 2-azabicyclo[2.2.1]hept-5-en-3-on LONZA AG (CH) 1995-02-15 EP claimed
EP-0424064-B1 Chiral azabicyloheptanone and a process for their preparation CHIROSCIENCE LTD (GB) 1995-02-08 EP claimed
EP-0628044-A1 THERAPEUTIC NUCLEOSIDES THE WELLCOME FOUNDATION LIMITED (GB) 1994-12-14 EP claimed
US-5284769-A Process for preparing a single enantiomer of a lactam using lactamase CHIROS LTD. (GB) 1994-02-08 US claimed
WO-1993017020-A2 THERAPEUTIC NUCLEOSIDES THE WELLCOME FOUNDATION LIMITED (GB) 1993-09-02 WO claimed
US-5200527-A Diels-Alder reaction of methanesulfonyl cyanide and cyclopentadiene, hydrolysis of product LONZA LTD. (CH) 1993-04-06 US claimed
EP-0508352-A1 Process for the preparation of 2-azabicyclo[2.2.1]hept-5-en-3-on LONZA AG (CH) 1992-10-14 EP claimed
EP-0424064-A1 Chiral azabicyloheptanone and a process for their preparation Chiroscience Limited (GB) 1991-04-24 EP claimed
US-4268672-A PREPARATION OF 5-AMINO-4N-(2,3B-DIHYDROXY-4-(HYDROXYMETHYL) CYCLOPENT-1-YL)AMINO-6-CHLOROPYRIMIDINE, CYCLIZATION, AND HALOGEN SUBSTITUTION THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1981-05-19 US claimed
US-4138562-A ANTITUMOR AGENTS, VIRICIDES THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1979-02-06 US claimed