Noreximide

Noreximide

SCHEMBL339739

O=C1NC(=O)C2C3C=CC(C3)C12

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TDP1 Q9NUW8 2/20 0.48
RAB9A P51151 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
RECQL P46063 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
USP2 O75604 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 1/20 0.38
KDM4E B2RXH2 2/20 0.37
MAPK1 P28482 1/20 0.37
MAPT P10636 2/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Noreximide SCHEMBL16664270 1.00 ALDH1A1 (0.48) ALDH1A1TDP1RAB9AMEN1KMT2A
Noreximide SCHEMBL2109030 1.00 ALDH1A1 (0.48) ALDH1A1TDP1RAB9AMEN1KMT2A
Noreximide SCHEMBL572054 1.00 ALDH1A1 (0.48) ALDH1A1TDP1RAB9AMEN1KMT2A
Noreximide SCHEMBL1105956 1.00 ALDH1A1 (0.48) ALDH1A1TDP1RAB9AMEN1KMT2A
Noreximide SCHEMBL14536593 1.00 ALDH1A1 (0.48) ALDH1A1TDP1RAB9AMEN1KMT2A
Noreximide SCHEMBL24120970 1.00 ALDH1A1 (0.48) ALDH1A1TDP1RAB9AMEN1KMT2A
Noreximide SCHEMBL17369118 1.00 ALDH1A1 (0.48) ALDH1A1TDP1RAB9AMEN1KMT2A
Noreximide SCHEMBL9073180 1.00 ALDH1A1 (0.48) ALDH1A1TDP1RAB9AMEN1KMT2A
Noreximide SCHEMBL17875126 1.00 ALDH1A1 (0.48) ALDH1A1TDP1RAB9AMEN1KMT2A
SCHEMBL16275149 0.88 ALDH1A1 (0.39) ALDH1A1TDP1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036591-A Production method of hexafluorophosphate product 河北圣泰材料股份有限公司 2026-05-15 CN claimed
US-20260115329-A1 BIORESORBABLE CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 US claimed
WO-2026090380-A1 BIORESORBABLE CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 WO claimed
US-20260041822-A1 Bottlebrush and Multi-Arm Polymers for Medical Applications BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-12 US claimed
US-20250345488-A1 CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-11-13 US claimed
EP-4607278-A1 CHEMICALLY-AMPLIFIED POSITIVE PHOTORESIST COMPOSITION FOR PATTERN PROFILE IMPROVEMENT AND ETCH RESISTANCE ENHANCEMENT Ycchem Co., Ltd. (KR) 2025-08-27 EP claimed
CN-120192263-A Preparation of 2- (endo-5-norbornene-2, 3-dicarboximide) -1, 3-tetramethylurea hexafluorophosphate 张家港市国泰华荣化工新材料有限公司 2025-06-24 CN claimed
US-20250199405-A1 CHEMICALLY-AMPLIFIED POSITIVE PHOTORESIST COMPOSITION FOR PATTERN PROFILE IMPROVEMENT AND ETCH RESISTANCE ENHANCEMENT YCCHEM CO., LTD. (KR) 2025-06-19 US claimed
CN-120136859-A Binaphthyl structure-assisted chiral pyridine oxazoline ligand, preparation method and application thereof 华东理工大学 2025-06-13 CN claimed
CN-119019649-B Cycloolefin polymer and preparation method thereof 中石油(上海)新材料研究院有限公司 2025-06-03 CN claimed
WO-2008106334-A2 FLAME RETARDED STYRENIC POLYMER FOAMS AND FOAM PRECURSORS ALBEMARLE CORPORATION (US) 2008-09-04 WO claimed
US-20080050631-A1 Fuel Cell System and Composition for Electrode NISSAN MOTOR CO., LTD. 2008-02-28 US claimed
US-20080044709-A1 Fuel Cell System and Solid Polymer Electrolyte Film NISSAN MOTOR CO., LTD. 2008-02-21 US claimed
EP-1042315-B1 CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS KLINGE CO CHEM PHARM FAB (DE) 2004-04-14 EP claimed
EP-0307553-B1 Modified splenopentines, their process of preparation and their use BERLIN CHEMIE AG (DE) 1994-06-15 EP claimed
US-5278246-A Radial base block copolymer of monovinyl aromatic hydrocarbon polymer blocks and an olefin compound polymer block composed mainly of conjugated diene, diene moiety being hydrogenated; at least one unsaturated dicarboxylic acid unit grafted to it ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-01-11 US claimed
US-4966923-A CONTAINING (METH)ALKYL SUBSTITUTED BICYCLO(2.2.1)HEP-5-ENE-2,3-DICARBOXYLIC ACID IMIDE AND ACRYLATED ESTER CIBA-GEIGY CORPORATION (US) 1990-10-30 US claimed
EP-0371001-A2 A modified block copolymer Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-05-30 EP claimed
EP-0262691-A2 A modified block copolymer Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-04-06 EP claimed
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041822-A1 Bottlebrush and Multi-Arm Polymers for Medical Applications BRDT, CD44, KLK3 ALDH1A1 220/4885TDP1 3463/4885RAB9A 4718/4885
US-20260115329-A1 BIORESORBABLE CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS RAD54L, EGFR, ARG1 ALDH1A1 334/4885TDP1 1151/4885RAB9A 1174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.