SCHEMBL5486185

SCHEMBL5486185

O=C(O)c1cccc(N=Nc2ccccc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.67
RAB9A P51151 7/20 0.61
NPC1 O15118 6/20 0.61
MAPT P10636 5/20 0.61
KMT2A Q03164 4/20 0.61
MEN1 O00255 3/20 0.61
L3MBTL1 Q9Y468 3/20 0.61
ALDH1A1 P00352 2/20 0.61
POLB P06746 2/20 0.61
GAA P10253 1/20 0.61
THRB P10828 1/20 0.61
PLCG1 P19174 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.58
GFER P55789 1/20 0.57
GLA P06280 1/20 0.56
CCNE2 O96020 1/20 0.56
CCNE1 P24864 1/20 0.56
CDK2 P24941 1/20 0.56
KDM4E B2RXH2 1/20 0.56
APEX1 P27695 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14437429 1.00 TRPA1 (0.67) TRPA1RAB9ANPC1MAPTKMT2A
SCHEMBL31045928 0.96 RAB9A (0.65) TRPA1RAB9ANPC1MAPTKMT2A
SCHEMBL69865 0.96 RAB9A (0.65) TRPA1RAB9ANPC1MAPTKMT2A
SCHEMBL69866 0.96 RAB9A (0.65) TRPA1RAB9ANPC1MAPTKMT2A
Azobenzene SCHEMBL28778962 0.94 TRPA1 (0.69) TRPA1RAB9ANPC1MAPTKMT2A
SCHEMBL7708935 0.90 MAPT (0.60) TRPA1RAB9ANPC1MAPTKMT2A
SCHEMBL7708937 0.90 MAPT (0.60) TRPA1RAB9ANPC1MAPTKMT2A
SCHEMBL16678896 0.89 MAPT (0.63) TRPA1RAB9ANPC1MAPTKMT2A
SCHEMBL15129042 0.89 MAPT (0.63) TRPA1RAB9ANPC1MAPTKMT2A
SCHEMBL11577315 0.87 MAPT (0.57) TRPA1RAB9ANPC1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007107775-A2 PREPARATION OF OLIGONUCLEOTIDES WITH PHOTOSWITCHABLE PROPERTIES THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2007-09-27 WO disclosed