Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 5/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261654 | 0.84 | SCN9A (0.35) | PIK3CAMTORCRHR1MAPK10IDH1 | |
| SCHEMBL5692224 | 0.82 | PIK3CA (0.37) | ALDH1A1PIK3CAMTORCRHR1MAPK10 | |
| SCHEMBL5176620 | 0.82 | ALDH1A1 (0.37) | ALDH1A1PIK3CAMTORCRHR1MAPK10 | |
| SCHEMBL5175915 | 0.82 | CMA1 (0.35) | PIK3CAMTORIDH1CMA1HTR1A | |
| SCHEMBL5158447 | 0.81 | ALDH1A1 (0.36) | ALDH1A1PIK3CAMTORCRHR1MAPK10 | |
| SCHEMBL293506 | 0.77 | PIK3CA (0.39) | PIK3CAMTORCRHR1MAPK10CMA1 | |
| SCHEMBL294265 | 0.76 | PIK3CA (0.43) | PIK3CAMTORCRHR1MAPK10CMA1 | |
| SCHEMBL512006 | 0.76 | PIK3CA (0.39) | PIK3CAMTORCMA1PDE10AAPLNR | |
| SCHEMBL17151142 | 0.75 | PIK3CA (0.47) | ALDH1A1PIK3CAMTORCMA1PDE10A | |
| SCHEMBL5800891 | 0.75 | PIK3CA (0.43) | PIK3CAMTORCRHR1MAPK10IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1629824-A1 | New coupler components | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-03-01 | — | — | EP | claimed |
| US-20060000032-A1 | Novel coupling components | HENKEL AG & CO. KGAA (DE) | 2006-01-05 | — | — | US | claimed |
| EP-1517669-B1 | NOVEL COUPLING COMPONENTS | HENKEL KGAA (DE) | 2005-10-26 | — | — | EP | claimed |
| US-7211119-B2 | Coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-05-01 | — | — | US | disclosed |
| EP-1647266-A1 | New coupler components | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-04-19 | — | — | EP | disclosed |
| EP-1629824-A1 | New coupler components | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-03-01 | — | — | EP | disclosed |
| EP-1629824-A1 | New coupler components | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-03-01 | — | — | EP | disclosed |
| US-20060000032-A1 | Novel coupling components | HENKEL AG & CO. KGAA (DE) | 2006-01-05 | — | — | US | disclosed |
| EP-1517669-B1 | NOVEL COUPLING COMPONENTS | HENKEL KGAA (DE) | 2005-10-26 | — | — | EP | disclosed |
| EP-1517669-A1 | NOVEL COUPLING COMPONENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004058204-A1 | NOVEL COUPLING COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060000032-A1 | Novel coupling components | KRT18, C9, H1-4 | ALDH1A1 450/4885PIK3CA 4334/4885MTOR 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.