Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5176620 | 0.95 | ALDH1A1 (0.37) | ALDH1A1CRHR1PIK3CAMTORMAPK10 | |
| SCHEMBL5692224 | 0.86 | PIK3CA (0.37) | ALDH1A1CRHR1PIK3CAMTORMAPK10 | |
| SCHEMBL5486206 | 0.81 | ALDH1A1 (0.37) | ALDH1A1CRHR1PIK3CAMTORMAPK10 | |
| SCHEMBL5691400 | 0.78 | P2RX7 (0.39) | ALDH1A1PIK3CAMTORMAPK10MET | |
| Hydrochloric Acid SCHEMBL9461657 | 0.76 | HTR1A (0.34) | ALDH1A1CRHR1PIK3CAMTORMAPK10 | |
| SCHEMBL30602382 | 0.76 | P2RX7 (0.38) | CRHR1PIK3CAMTORMAPK10MET | |
| SCHEMBL29130967 | 0.76 | P2RX7 (0.38) | CRHR1PIK3CAMTORMAPK10MET | |
| SCHEMBL5175915 | 0.73 | CMA1 (0.35) | PIK3CAMTORIDH1PARP1 | |
| SCHEMBL6264641 | 0.73 | SYK (0.36) | ALDH1A1CRHR1PIK3CAMTORMAPK10 | |
| SCHEMBL9461697 | 0.72 | GRIN2D (0.43) | ALDH1A1PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748822-A1 | M-PHENYLENE DIAMINE COUPLING COMPONENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-02-07 | — | — | EP | claimed |
| WO-2005117819-A1 | M-PHENYLENE DIAMINE COUPLING COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-15 | — | — | WO | claimed |
| EP-1748822-A1 | M-PHENYLENE DIAMINE COUPLING COMPONENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005117819-A1 | M-PHENYLENE DIAMINE COUPLING COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-15 | — | — | WO | disclosed |