⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230684 | 0.85 | — | — | |
| SCHEMBL11317502 | 0.75 | — | — | |
| SCHEMBL6054235 | 0.74 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL9601537 | 0.69 | TP53 (0.48) | — | |
| SCHEMBL21987140 | 0.69 | TP53 (0.48) | — | |
| SCHEMBL3972585 | 0.67 | — | — | |
| SCHEMBL18670054 | 0.65 | — | — | |
| SCHEMBL10746978 | 0.60 | — | — | |
| SCHEMBL10749609 | 0.60 | — | — | |
| SCHEMBL9602259 | 0.59 | TP53 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223874-B2 | Bicyclic tetrahydrofuran lactone derivatives and process for the preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-05-29 | — | — | US | claimed |
| WO-2007007940-A1 | BICYCLIC TETRAHYDROFURAN LACTONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007938-A1 | TRICYCLIC TETRAHYDROFURAN LACTONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-01-18 | — | — | WO | claimed |
| US-20070010679-A1 | Bicyclic tetrahydrofuran lactone derivatives and process for the preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2007-01-11 | — | — | US | claimed |
| EP-0363230-B1 | USE OF ACETOGENINS IN THERAPY AS ANTIPARASITIC SUBSTANCES | LABORATOIRES DEBAT Société anonyme dite: (FR) | 1992-07-08 | — | — | EP | claimed |
| EP-0363230-A2 | Use of acetogenins in therapy as antiparasitic substances | LABORATOIRES DEBAT Société anonyme dite: (FR) | 1990-04-11 | — | — | EP | claimed |
| JP-2059525-A | — | — | None | — | — | JP | disclosed |
| CN-117790901-A | Additive, electrolyte and application of additive and electrolyte in secondary battery | 蓝固(淄博)新能源科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-103880788-A | Crystal form of tetrahydrofuran lactone ring derivative | UNIV CHENGDU TRAD CN MEDICINE | 2014-06-25 | — | — | CN | disclosed |
| US-20070270584-A1 | Process for the Preparation of Steroidal Carbothioic Acid Derivatives and Intermediates | AXELLIA PHARMACEUTICALS APS (DK) | 2007-11-22 | — | — | US | disclosed |
| US-7223874-B2 | Bicyclic tetrahydrofuran lactone derivatives and process for the preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-05-29 | — | — | US | disclosed |
| US-7223874-B2 | Bicyclic tetrahydrofuran lactone derivatives and process for the preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-05-29 | — | — | US | disclosed |
| US-7223874-B2 | Bicyclic tetrahydrofuran lactone derivatives and process for the preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-05-29 | — | — | US | disclosed |
| US-20070010679-A1 | Bicyclic tetrahydrofuran lactone derivatives and process for the preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2007-01-11 | — | — | US | disclosed |
| EP-1611149-A1 | PROCESS FOR THE PREPARATION OF STEROIDAL CARBOTHIOIC ACID DERIVATIVES AND INTERMEDIATES | Alpharma APS (DK) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004087731-A1 | PROCESS FOR THE PREPARATION OF STEROIDAL CARBOTHIOIC ACID DERIVATIVES AND INTERMEDIATES | ALPHARMA APS (DK) | 2004-10-14 | — | — | WO | disclosed |
| EP-0363230-B1 | USE OF ACETOGENINS IN THERAPY AS ANTIPARASITIC SUBSTANCES | LABORATOIRES DEBAT Société anonyme dite: (FR) | 1992-07-08 | — | — | EP | disclosed |
| EP-0363230-A2 | Use of acetogenins in therapy as antiparasitic substances | LABORATOIRES DEBAT Société anonyme dite: (FR) | 1990-04-11 | — | — | EP | disclosed |
| EP-0363230-A2 | Use of acetogenins in therapy as antiparasitic substances | LABORATOIRES DEBAT Société anonyme dite: (FR) | 1990-04-11 | — | — | EP | disclosed |
| JP-H0259525-A | THERAPEUTIC ANTIPARASITIC COMPRISING ACETOGENIN | LAB DEBAT | 1990-02-28 | — | — | JP | disclosed |