SCHEMBL9601537

SCHEMBL9601537

O=C1OC(=O)C2CCC1O2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.48
LMNA P02545 3/20 0.48
RAB9A P51151 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
KDM4E B2RXH2 2/20 0.48
GMNN O75496 2/20 0.48
PPM1B O75688 2/20 0.48
PPP1CC P36873 2/20 0.48
TFPI2 P48307 2/20 0.48
PPP5C P53041 2/20 0.48
PPP1CA P62136 2/20 0.48
PMP22 Q01453 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
NFKB1 P19838 2/20 0.48
THPO P40225 2/20 0.48
CYP2D6 P10635 1/20 0.48
CYP3A4 P08684 3/20 0.32
MAPK1 P28482 3/20 0.32
HIF1A Q16665 2/20 0.32
CYP1A2 P05177 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21987140 1.00 TP53 (0.48) TP53LMNARAB9ASMN1; SMN2KDM4E
SCHEMBL9602259 0.88 TP53 (0.44) TP53LMNARAB9ASMN1; SMN2KDM4E
SCHEMBL1664815 0.71 TP53 (0.33) TP53LMNARAB9ASMN1; SMN2KDM4E
SCHEMBL5486329 0.69
SCHEMBL125505 0.69 KDM4E (0.31) TP53LMNARAB9ASMN1; SMN2KDM4E
SCHEMBL14187990 0.68 KDM4E (0.38) TP53LMNARAB9ASMN1; SMN2KDM4E
SCHEMBL21999910 0.68 KDM4E (0.53) TP53LMNARAB9ASMN1; SMN2KDM4E
SCHEMBL910480 0.68 KDM4E (0.53) TP53LMNARAB9ASMN1; SMN2KDM4E
SCHEMBL112827 0.68 KDM4E (0.53) TP53LMNARAB9ASMN1; SMN2KDM4E
SCHEMBL19107418 0.68 KDM4E (0.53) TP53LMNARAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132106-A1 FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING CELLORAM, INC. (US) 2026-05-14 US disclosed
EP-4719369-A2 INHIBITORS OF FATTY ACID BINDING PROTEINS (FABPS), METHODS OF USE AND METHODS OF MAKING Celloram, Inc. (US) 2026-04-08 EP disclosed
US-12570603-B2 FABP4/5 inhibitors, methods of use and methods of making CELLORAM INC. (US) 2026-03-10 US disclosed
US-12514853-B2 Therapeutic dendrimer STARPHARMA PTY LTD. (AU) 2026-01-06 US disclosed
CN-113056469-B Therapeutic dendrimers 星法马私人有限公司 2025-05-23 CN disclosed
WO-2024254161-A2 INHIBITORS OF FATTY ACID BINDING PROTEINS (FABPS), METHODS OF USE AND METHODS OF MAKING CELLORAM INC. (US) 2024-12-12 WO disclosed
EP-4402132-A1 FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING Celloram, Inc. (US) 2024-07-24 EP disclosed
US-20230150931-A1 FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING NOVIUS THERAPEUTICS, LLC (US) 2023-05-18 US disclosed
US-20230150931-A1 FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING NOVIUS THERAPEUTICS, LLC (US) 2023-05-18 US disclosed
US-20230150931-A1 FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING NOVIUS THERAPEUTICS, LLC (US) 2023-05-18 US disclosed
WO-2023043803-A1 FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING NOVIUS THERAPEUTICS, LLC (US) 2023-03-23 WO disclosed
US-20220023290-A1 THERAPEUTIC DENDRIMER STARPHARMA PTY LTD. (AU) 2022-01-27 US disclosed
EP-3883934-A1 THERAPEUTIC DENDRIMER Starpharma Pty Limited (AU) 2021-09-29 EP disclosed
US-20200172532-A1 HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS JANSSEN PHARMACEUTICA NV (BE) 2020-06-04 US disclosed
EP-0309544-B1 PSYCHOTROPIC BICYCLIC IMIDES AMERICAN HOME PRODUCTS CORPORATION (US) 1993-02-10 EP disclosed
EP-0309544-A1 PSYCHOTROPIC BICYCLIC IMIDES. AMERICAN HOME PROD (US) 1989-04-05 EP disclosed
WO-1988007530-A1 PSYCHOTROPIC BICYCLIC IMIDES AMERICAN HOME PRODUCTS CORPORATION (US) 1988-10-06 WO disclosed
US-4748240-A Psychotropic bicyclic imides AMERICAN HOME PRODUCTS CORPORATION (US) 1988-05-31 US disclosed
US-4216215-A 7[(Furanyl-2-acetamido)-2-acetamido]cephalosporin derivatives PFIZER INC. (US) 1980-08-05 US disclosed
US-4137312-A Epoxy substituted cephalosporin derivatives PFIZER INC. (US) 1979-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220023290-A1 THERAPEUTIC DENDRIMER DCK, PAICS, DCLRE1A TP53 43/4885LMNA 753/4885RAB9A 1776/4885
US-12570603-B2 FABP4/5 inhibitors, methods of use and methods of making FABP5, FABP1, FABP4 TP53 1153/4885LMNA 2630/4885RAB9A 892/4885
US-20260132106-A1 FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING FABP5, FABP4, FABP1 TP53 1716/4885LMNA 2177/4885RAB9A 1822/4885
US-20200172532-A1 HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS HAVCR2, HCCS, PYGL TP53 513/4885LMNA 3136/4885RAB9A 2841/4885
US-20230150931-A1 FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING FABP5, FABP1, FABP4 TP53 746/4885LMNA 2368/4885RAB9A 3995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.