Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL45368 | 0.98 | — | — | |
| SCHEMBL4576636 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL2277860 | 0.95 | — | — | |
| Fluoride Ion SCHEMBL1130342 | 0.94 | — | — | |
| Bromide SCHEMBL28815501 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL2276757 | 0.93 | TDP1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL9581304 | 0.91 | ACHE (0.33) | — | |
| Hydrochloric Acid SCHEMBL4339155 | 0.91 | ACHE (0.33) | — | |
| Hydrochloric Acid SCHEMBL817879 | 0.90 | — | — | |
| Fluoride Ion SCHEMBL5085381 | 0.89 | TDP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337565-B1 | BIMETALLIC CATALYST FOR PRODUCING POLYETHYLENE RESINS WITH BIMODAL MOLECULAR WEIGHT DISTRIBUTION, ITS PREPARATION AND USE | UNIVATION TECH LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| US-7129302-B2 | Bimetallic catalyst for producing polyethylene resins with bimodal molecular weight distribution, its preparation and use | UNIVATION TECHNOLOGIES, LLC (US) | 2006-10-31 | — | — | US | disclosed |
| US-20050267271-A1 | Bimetallic catalyst for producing polyethylene resins with bimodal molecular weight distribution, its preparation and use | MINK ROBERT I | 2005-12-01 | — | — | US | disclosed |
| US-6964937-B2 | Bimetallic catalyst for producing polyethylene resins with bimodal molecular weight distribution, its preparation and use | UNIVATION TECHNOLOGIES, LLC (US) | 2005-11-15 | — | — | US | disclosed |
| US-20040048736-A1 | Bimetallic catalyst for producing polyethylene resins with bimodal molecular weight distribution, its preparation and use | UNIVATION TECHNOLOGIES, LLC | 2004-03-11 | — | — | US | disclosed |
| EP-1337565-A1 | BIMETALLIC CATALYST FOR PRODUCING POLYETHYLENE RESINS WITH BIMODAL MOLECULAR WEIGHT DISTRIBUTION, ITS PREPARATION AND USE | ExxonMobil Chemical Patents Inc. (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0977786-B1 | PREMIUM PIPE RESINS | EXXONMOBIL OIL CORP (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6403181-B1 | CONDUITS MADE FROM POLYETHYLENE MIXTURES HAVING BIMODAL MOLECULAR WEIGHT DISTRIBUTION, HIGH MOLECULAR WEIGHT AND HIGH VISCOSITY; IMPACT/TENSILE STRENGTH; VIABILITY | MOBIL OIL CORPORATION | 2002-06-11 | — | — | US | disclosed |
| WO-2002044222-A1 | BIMETALLIC CATALYST FOR PRODUCING POLYETHYLENE RESINS WITH BIMODAL MOLECULAR WEIGHT DISTRIBUTION, ITS PREPARATION AND USE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-06-06 | — | — | WO | disclosed |
| EP-0977786-A4 | PREMIUM PIPE RESINS | MOBIL OIL CORP (US) | 2001-10-24 | — | — | EP | disclosed |
| EP-0977786-A1 | PREMIUM PIPE RESINS | MOBIL OIL CORPORATION (a New York corporation) (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049209-A1 | PREMIUM PIPE RESINS | MOBIL OIL CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |