Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486419 | 0.80 | CYP2C19 (0.58) | RAB9ANPC1KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL4064076 | 0.75 | MEN1 (0.58) | CYP1A2RAB9ANPC1KCNQ3KCNQ2 | |
| SCHEMBL14534679 | 0.74 | KCNQ3 (0.43) | KCNQ3KCNQ2MAPK3MAPK1 | |
| SCHEMBL4551615 | 0.73 | PDE4B (0.45) | CYP1A2RAB9AKCNQ3KCNQ2MAPK3 | |
| SCHEMBL4551616 | 0.73 | MAPK14 (0.49) | KCNQ3KCNQ2PDE4B | |
| SCHEMBL23245969 | 0.73 | KCNQ3 (0.45) | KCNQ3KCNQ2MAPK3MAPK1FYN | |
| SCHEMBL14534694 | 0.72 | MAPK14 (0.45) | RAB9ANPC1KCNQ3KCNQ2TP53 | |
| SCHEMBL4414329 | 0.72 | BRAF (0.43) | KCNQ3KCNQ2 | |
| SCHEMBL4551772 | 0.72 | PDE4B (0.43) | CYP1A2RAB9ANPC1KCNQ3KCNQ2 | |
| SCHEMBL5490015 | 0.71 | RAF1 (0.52) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |