Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483905 | 0.85 | CYP2C19 (0.54) | CYP2C19SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL5486398 | 0.80 | CYP1A2 (0.46) | SMN1; SMN2RAB9ANPC1TP53LMNA | |
| SCHEMBL5486403 | 0.79 | MLYCD (0.46) | SMN1; SMN2RAB9ANPC1TP53ALOX15 | |
| SCHEMBL5483909 | 0.78 | SMN1; SMN2 (0.53) | CYP2C19SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL5083468 | 0.78 | ALDH1A1 (0.65) | SMN1; SMN2RAB9ATP53ALDH1A1MAPT | |
| SCHEMBL23245969 | 0.74 | KCNQ3 (0.45) | KCNQ3KCNQ2 | |
| SCHEMBL29634591 | 0.73 | ALDH1A1 (0.59) | CYP2C19SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL23387883 | 0.73 | ALDH1A1 (0.59) | CYP2C19SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL1571386 | 0.72 | LMNA (1.00) | RAB9ANPC1LMNAHIF1AGAA | |
| SCHEMBL18979462 | 0.72 | SMN1; SMN2 (0.52) | CYP2C19SMN1; SMN2RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |