Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447466 | 0.84 | KMT2A (0.36) | TAAR1IDO1ALDH1A1LMNACYP1A2 | |
| SCHEMBL7754170 | 0.80 | TAAR1 (0.52) | TAAR1IDO1ACHECYP11B1CYP11B2 | |
| SCHEMBL5488915 | 0.79 | TAAR1 (0.57) | TAAR1IDO1ACHECYP11B1CYP11B2 | |
| SCHEMBL16621914 | 0.77 | TAAR1 (0.48) | TAAR1IDO1ACHECYP11B1CYP11B2 | |
| SCHEMBL5488290 | 0.77 | CYP11B1 (0.36) | CYP11B1CYP11B2ALDH1A1LMNAHTT | |
| SCHEMBL2819082 | 0.76 | TAAR1 (0.52) | TAAR1IDO1ACHECYP11B1CYP11B2 | |
| SCHEMBL13027235 | 0.75 | IDO1 (0.50) | TAAR1IDO1ACHECYP11B1CYP11B2 | |
| SCHEMBL52147 | 0.75 | — | — | |
| SCHEMBL30084583 | 0.75 | — | — | |
| SCHEMBL29596752 | 0.74 | TAAR1 (0.74) | TAAR1IDO1ACHEHRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |