SCHEMBL7754170

SCHEMBL7754170

Cc1cccc(C[Si](C)(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.52
IDO1 P14902 2/20 0.50
ACHE P22303 1/20 0.48
CYP11B1 P15538 2/20 0.44
CYP11B2 P19099 2/20 0.44
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43
MAOB P27338 2/20 0.42
ESR1 P03372 1/20 0.41
CTBP2 P56545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5486477 0.80 TAAR1 (0.50) TAAR1IDO1ACHECYP11B1CYP11B2
SCHEMBL7245079 0.79 TAAR1 (0.36) TAAR1IDO1ACHECYP11B1CYP11B2
SCHEMBL16621914 0.78 TAAR1 (0.48) TAAR1IDO1ACHECYP11B1CYP11B2
SCHEMBL13027235 0.77 IDO1 (0.50) TAAR1IDO1ACHECYP11B1CYP11B2
SCHEMBL8861689 0.76 PRKCI (0.46) CYP11B1CYP11B2ESR1
SCHEMBL8861703 0.76 TAAR1 (0.50) TAAR1IDO1CYP11B1CYP11B2ALDH1A1
SCHEMBL751327 0.75 ESR1 (0.42) CYP11B1CYP11B2ALDH1A1ESR1
SCHEMBL748390 0.75 ESR1 (0.42) ACHECYP11B1CYP11B2ALDH1A1ESR1
SCHEMBL30000562 0.75 TAAR1 (0.60) TAAR1IDO1ACHEALDH1A1HRH3
SCHEMBL29596752 0.75 TAAR1 (0.74) TAAR1IDO1ACHEHRH3MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3772517-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME, AND DIAGNOSTIC COMPOSITION INCLUDING SAME SAMSUNG ELECTRONICS CO LTD (KR) 2022-11-02 EP disclosed
US-20220290019-A1 CURABLE FLUOROPOLYETHER ADHESIVE COMPOSITION AND OPTICAL PARTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-09-15 US disclosed
US-20210403709-A1 CURABLE FLUOROPOLYETHER-BASED RUBBER COMPOSITION AND OPTICAL COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-12-30 US disclosed
CN-107207632-B Process for producing modified conjugated diene rubber 日本瑞翁株式会社 2020-04-14 CN disclosed
US-10017677-B2 Heat-conductive fluorinated curable composition, cured product thereof, and electric/electronic part SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-07-10 US disclosed
US-20170121583-A1 HEAT-CONDUCTIVE FLUORINATED CURABLE COMPOSITION, CURED PRODUCT THEREOF, AND ELECTRIC/ELECTRONIC PART SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-04 US disclosed
US-20160053033-A1 METHOD OF PRODUCTION OF RADIAL CONJUGATED DIENE RUBBER ZEON CORPORATION (JP) 2016-02-25 US disclosed
CN-105073808-A Method for producing radial conjugated diene rubber ZEON CORP 2015-11-18 CN disclosed
WO-2001066248-A2 C-C AND C-N COUPLING CATALYST COMPRISING TRANSITION METAL AND CARBENE UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION (US) 2001-09-13 WO disclosed