Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL18394201 | 0.82 | LMNA (0.46) | TAAR1IDO1CNR1ACHE | |
| SCHEMBL29596752 | 0.80 | TAAR1 (0.74) | TAAR1HRH3IDO1DAOACHE | |
| SCHEMBL8096473 | 0.80 | TAAR1 (0.74) | TAAR1HRH3IDO1DAOACHE | |
| SCHEMBL5486477 | 0.79 | TAAR1 (0.50) | TAAR1HRH3IDO1ACHECYP11B1 | |
| SCHEMBL28672310 | 0.78 | TAAR1 (0.55) | TAAR1MMP13HRH3IDO1CNR1 | |
| SCHEMBL5486678 | 0.78 | TAAR1 (0.59) | TAAR1IDO1 | |
| SCHEMBL4839367 | 0.78 | TSHR (0.40) | TAAR1 | |
| SCHEMBL25448924 | 0.77 | TAAR1 (0.53) | TAAR1MMP13HRH3IDO1CNR1 | |
| SCHEMBL13027403 | 0.77 | TAAR1 (0.53) | TAAR1MMP13HRH3IDO1DAO | |
| SCHEMBL296315 | 0.77 | TAAR1 (0.63) | TAAR1HRH3IDO1DAOACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |