Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | SNCA | P37840 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951161 | 0.89 | SNCA (0.67) | MEN1KMT2ASNCANPC1ALDH1A1 | |
| SCHEMBL8334964 | 0.82 | ALOX5 (0.70) | ALOX5MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7875424 | 0.81 | ALOX5 (0.68) | ALOX5MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6864203 | 0.80 | ALOX5 (0.67) | ALOX5MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL28328243 | 0.80 | MEN1 (0.70) | ALOX5MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL29594517 | 0.77 | MEN1 (0.73) | ALOX5MEN1KMT2AMAPT | |
| SCHEMBL30758797 | 0.77 | SNCA (0.59) | MEN1KMT2ASNCANPC1MAPT | |
| SCHEMBL4081845 | 0.77 | SNCA (0.59) | MEN1KMT2ASNCANPC1MAPT | |
| SCHEMBL14290087 | 0.77 | TOP1 (0.73) | MEN1KMT2ASNCANPC1ALDH1A1 | |
| SCHEMBL10904297 | 0.76 | ALOX5 (1.00) | ALOX5MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |
| EP-0948483-B1 | FARNESYL TRANSFERASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2002-03-13 | — | — | EP | disclosed |