SCHEMBL5486517

SCHEMBL5486517

CC(C)CCC(COC(=O)c1ccccc1)C(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
ADRB2 P07550 2/20 0.54
ADRB1 P08588 2/20 0.54
ADRB3 P13945 2/20 0.54
TSHR P16473 3/20 0.49
LMNA P02545 1/20 0.49
TDP1 Q9NUW8 2/20 0.47
MAPT P10636 1/20 0.46
MAPK1 P28482 2/20 0.46
HIF1A Q16665 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 1/20 0.46
PLA2G1B P04054 1/20 0.46
ATG4B Q9Y4P1 1/20 0.46
SLC1A5 Q15758 1/20 0.44
PRKCA P17252 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14956200 0.90 ALDH1A1 (0.65) ALDH1A1ADRB2ADRB1ADRB3TSHR
SCHEMBL5486475 0.89 MAPT (0.51) ALDH1A1ADRB2ADRB1ADRB3TSHR
SCHEMBL19348901 0.85 TSHR (0.69) ALDH1A1ADRB2ADRB1ADRB3TSHR
SCHEMBL570914 0.85 ALDH1A1 (0.59) ALDH1A1ADRB2ADRB1ADRB3TSHR
Benzoic Acid 2-Methylpropyl Ester SCHEMBL20530394 0.83 TSHR (0.69) ALDH1A1ADRB2ADRB1ADRB3TSHR
Benzoic Acid 2-Methylpropyl Ester SCHEMBL298176 0.83 TSHR (0.69) ALDH1A1ADRB2ADRB1ADRB3TSHR
Benzoic Acid 2-Methylpropyl Ester SCHEMBL27827529 0.81 TSHR (0.67) ALDH1A1ADRB2ADRB1ADRB3TSHR
Benzoic Acid 2-Methylpropyl Ester SCHEMBL28242226 0.81 TSHR (0.67) ALDH1A1ADRB2ADRB1ADRB3TSHR
SCHEMBL5476291 0.80 ALDH1A1 (0.53) ALDH1A1ADRB2ADRB1ADRB3TSHR
SCHEMBL5484090 0.80 MAPT (0.57) ALDH1A1ADRB2ADRB1ADRB3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7205349-B2 Isodecyl benzoate mixtures, preparation, and their use OXENO OLEFINCHEMIE GMBH (DE) 2007-04-17 US claimed
EP-1415978-B1 Benzoic acid isodecyl ester mixtures, process for their preparation and their use OXENO OLEFINCHEMIE GMBH (DE) 2006-02-22 EP claimed
US-20040138358-A1 Isodecyl benzoate mixtures, preparation, and their use EVONIK DEGUSSA GMBH (DE) 2004-07-15 US claimed
US-7205349-B2 Isodecyl benzoate mixtures, preparation, and their use OXENO OLEFINCHEMIE GMBH (DE) 2007-04-17 US disclosed
US-20040138358-A1 Isodecyl benzoate mixtures, preparation, and their use EVONIK DEGUSSA GMBH (DE) 2004-07-15 US disclosed