Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5476291 | 0.91 | ALDH1A1 (0.53) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL5486517 | 0.85 | ALDH1A1 (0.57) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL561339 | 0.85 | ALDH1A1 (0.61) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL570395 | 0.85 | ALDH1A1 (0.66) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL20530394 | 0.84 | TSHR (0.69) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL298176 | 0.84 | TSHR (0.69) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL12000806 | 0.84 | ALDH1A1 (0.74) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL28242226 | 0.82 | TSHR (0.67) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL27827529 | 0.82 | TSHR (0.67) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL570998 | 0.82 | ALDH1A1 (0.66) | ALDH1A1ADRB2ADRB1ADRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601224-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2018-09-19 | — | — | EP | disclosed |
| EP-2601224-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2013-06-12 | — | — | EP | disclosed |
| US-20130131290-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2013-05-23 | — | — | US | disclosed |
| WO-2012017040-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2012-02-09 | — | — | WO | disclosed |