Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616898 | 0.79 | DDR1 (0.40) | HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL29637752 | 0.74 | DDR1 (0.40) | HTT | |
| SCHEMBL20577192 | 0.74 | POLB (0.34) | HTT | |
| Hydrochloric Acid SCHEMBL3822769 | 0.73 | POLB (0.33) | HTT | |
| Hydrochloric Acid SCHEMBL5008312 | 0.73 | DDR1 (0.39) | HTT | |
| Hydrochloric Acid SCHEMBL3820275 | 0.73 | POLB (0.33) | HTT | |
| SCHEMBL3828653 | 0.71 | ELANE (0.43) | HTTHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL4528112 | 0.71 | HSD17B10 (0.37) | HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL3826604 | 0.70 | LMNA (0.36) | HTTMAPT | |
| SCHEMBL9049182 | 0.70 | DDR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709019-B1 | THIAZOLE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS (AN) | 2007-08-08 | — | — | EP | disclosed |