SCHEMBL9049182

SCHEMBL9049182

CC(=O)C(Cl)C(C)=O.CCc1nc(C)c(C(C)=O)o1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 1/20 0.38
DGAT1 O75907 2/20 0.34
GAA P10253 1/20 0.32
NTRK1 P04629 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8616898 0.88 DDR1 (0.40) DDR1DGAT1GAANTRK1
SCHEMBL597035 0.76 DDR1 (0.41) DDR1DGAT1GAANTRK1
SCHEMBL5486555 0.70 HTT (0.38)
SCHEMBL16434272 0.67 CA9 (0.35) DDR1
SCHEMBL4528112 0.63 HSD17B10 (0.37) GAA
SCHEMBL16440380 0.62 CYP1A2 (0.40) GAA
SCHEMBL18603033 0.62 TSHR (0.42)
SCHEMBL53472 0.61
SCHEMBL1532490 0.61
SCHEMBL9917050 0.60 HCAR2 (0.39) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707584-A1 NOVEL (1-HETEROAZOLYL-1-HETEROCYCLYL)ALKANE DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE AGENTS Astra Aktiebolag (SE) 1996-04-24 EP disclosed