SCHEMBL5486596

SCHEMBL5486596

CC1(N)C=CC(N)=CC1.Cc1cc(N)ccc1N

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
CYP3A4 P08684 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
CASP1 P29466 2/20 0.36
TSHR P16473 2/20 0.36
PDE10A Q9Y233 1/20 0.34
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
THRB P10828 2/20 0.32
KMT2A Q03164 2/20 0.32
GAA P10253 1/20 0.32
NR4A1 P22736 1/20 0.32
PTK2B Q14289 1/20 0.32
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
ALOX15 P16050 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
S100B P04271 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33699 0.81
Hydrochloric Acid SCHEMBL7196448 0.79 NOS3 (0.31)
Bromide SCHEMBL30537821 0.79 NOS3 (0.31)
Hydrochloric Acid SCHEMBL7637452 0.79 NOS3 (0.31)
SCHEMBL29466927 0.77 ALDH1A1 (0.36) ALDH1A1CYP3A4CASP1TSHRPDE10A
Formaldehyde SCHEMBL29142549 0.76
SCHEMBL301921 0.75 ALDH1A1 (0.48) ALDH1A1CYP3A4TDP1TSHRMAPT
SCHEMBL29948032 0.75 ALDH1A1 (0.48) ALDH1A1CYP3A4TDP1TSHRMAPT
SCHEMBL30447195 0.73 ALDH1A1 (0.37) ALDH1A1CYP3A4TDP1TSHRS100B
SCHEMBL4872121 0.73 ALDH1A1 (0.65) ALDH1A1CYP3A4TDP1CASP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070017041-A1 Colorants for keratin fibres PROCTER & GAMBLE COMPANY, THE 2007-01-25 US disclosed