SCHEMBL5486613

SCHEMBL5486613

CC(CCC(=O)S)NC(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 2/20 0.53
ATM Q13315 1/20 0.53
CTSK P43235 6/20 0.51
ELANE P08246 1/20 0.50
CTSS P25774 4/20 0.49
CTSL P07711 3/20 0.49
CTSB P07858 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265046 0.89 ATM (0.56) CTRB1ATMCTSKELANECTSS
SCHEMBL8061660 0.89 ATM (0.56) CTRB1ATMCTSKELANECTSS
SCHEMBL265604 0.89 ATM (0.56) CTRB1ATMCTSKELANECTSS
SCHEMBL12935869 0.86 CTSK (0.54) CTRB1ATMCTSKELANE
SCHEMBL5486617 0.86 ATM (0.53) CTRB1ATMCTSKELANECTSS
SCHEMBL28297328 0.85 ATM (0.52) CTRB1ATMCTSKELANECTSS
SCHEMBL18857044 0.84 SMN1; SMN2 (0.62) ATMCTSL
SCHEMBL15414625 0.84 ATM (0.57) CTRB1ATMCTSKELANECTSS
SCHEMBL938011 0.84 ATM (0.57) CTRB1ATMCTSKELANECTSS
SCHEMBL938009 0.84 ATM (0.57) CTRB1ATMCTSKELANECTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7161032-B2 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO., LTD. (JP) 2007-01-09 US disclosed
US-20060167315-A1 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO., LTD. (JP) 2006-07-27 US disclosed
EP-1544193-A1 SULFONAMIDE DERIVATIVES, INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2005-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167315-A1 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof CBR3, CNPY2, STS CTRB1 603/4885ATM 3906/4885CTSK 2315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.