Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 5/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265604 | 0.90 | ATM (0.56) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL8061660 | 0.90 | ATM (0.56) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL265046 | 0.90 | ATM (0.56) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL26088846 | 0.87 | SIRT2 (0.50) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL26088808 | 0.86 | ATM (0.54) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL22321302 | 0.86 | ATM (0.54) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL22321304 | 0.86 | ATM (0.54) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL5486613 | 0.85 | CTRB1 (0.53) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL5486617 | 0.85 | ATM (0.53) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL12935869 | 0.85 | CTSK (0.54) | ATMCTSKELANECTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689654-A | 7-substituted 1-pyridyl-naphthyridine-3-carboxamides and their use | 拜耳医药股份有限公司 | 2019-04-26 | — | — | CN | disclosed |